What is the NOAEL for 1,4-Benzenedicarboxaldehyde?
1,4-Benzenedicarboxaldehyde has 4 NOAEL studies in the database. The lowest reported value is M2Y6E4N2TS UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
1,4-Benzenedicarboxaldehyde
Also known as: EINECS 210-784-8, p-Phthalaldehyde, Terephtaldehyde, Terephthaldehyde, Terephtaldehydes
CAS 623-27-8
1,4-Benzenedicarboxaldehyde (CAS 623-27-8) is a chemical substance. Key regulatory status: REACH registered, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
Cross-Vertical Regulatory Divergence
1,4-Benzenedicarboxaldehyde is classified GHS Danger (H302, H311, H315, H319, H331, H335) in the chemicals database but is restricted in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
0
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
11 fields
Name
1,4-Benzenedicarboxaldehyde
CAS Number
623-27-8
DTXSID
DTXSID6060769
Molecular Formula
C8H6O2
InChI Key
KUCOHFSKRZZVRO-UHFFFAOYSA-N
Monoisotopic Mass
134.036779
Synonyms
EINECS 210-784-8p-PhthalaldehydeTerephtaldehydeTerephthaldehydeTerephtaldehydes
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
1 records
Preservative
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| M2Y6E4N2TS | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| M2Y6E4N2TS | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| M2Y6E4N2TS | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| M2Y6E4N2TS | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Terephthalaldehyde | 210-784-8 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
restricted
Max
-
Category
Cosmetic Ingredient
Frequently Asked Questions
Is 1,4-Benzenedicarboxaldehyde used in cosmetics?
Yes, 1,4-Benzenedicarboxaldehyde is also indexed as a cosmetic ingredient under the name Terephthalaldehyde. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 1,4-Benzenedicarboxaldehyde come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
Does 1,4-Benzenedicarboxaldehyde have different safety status in cosmetics vs industrial chemicals?
1,4-Benzenedicarboxaldehyde is classified GHS Danger (H302, H311, H315, H319, H331, H335) in the chemicals database but is restricted in EU cosmetics.
Is 1,4-Benzenedicarboxaldehyde used outside industrial chemicals?
1,4-Benzenedicarboxaldehyde also appears in cosmetics databases.