Is Terephthalaldehyde safe in cosmetics?
Terephthalaldehyde has a safety rating of "POOR" in our database. EU status: restricted. US status: permitted.
Poor
Cosmetic Ingredient
Terephthalaldehyde
Also known as: EINECS 210-784-8, p-Phthalaldehyde, Terephtaldehyde, Terephthaldehyde, Terephtaldehydes
INCI: TEREPHTHALALDEHYDE
Terephthalaldehyde (CAS 623-27-8) is a cosmetic cosmetic ingredient functioning as Not a typical cosmetic active — this is a dialdehyde. EU Regulation 1223/2009 status: restricted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 623-27-8 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Terephthalaldehyde is classified GHS Danger (H302, H311, H315, H319, H331, H335) in the chemicals database but is restricted in EU cosmetics.
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Not a typical cosmetic active — this is a dialdehyde (benzene-1,4-dicarbaldehyde), potentially used as a cross-linker or fixative
Safety Rating
POOR
Chemistry & Identifiers
IUPAC Name
terephthalaldehyde
InChIKey
KUCOHFSKRZZVRO-UHFFFAOYSA-N
Regulatory Status
EU EU Status
restricted
US US Status
permitted
US Notes
Not specifically addressed for cosmetic use
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Terephthalaldehyde.
Calculate MoS for your specific formulation with the MoS Calculator.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
1 - 10 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Preservative
Expert Verdict
Expert safety assessment and concern-level summary for Terephthalaldehyde.
Regulatory Flags
potential-allergen
Known Synonyms
EINECS 210-784-8
p-Phthalaldehyde
Terephtaldehyde
Terephthaldehyde
Terephtaldehydes
Chemical Function
Preservative
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Terephthalaldehyde allowed in the EU?
Terephthalaldehyde EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.
What does Terephthalaldehyde do in cosmetics?
Terephthalaldehyde functions as: Not a typical cosmetic active — this is a dialdehyde (benzene-1,4-dicarbaldehyde), potentially used as a cross-linker or fixative. It is classified as a cosmetic ingredient in our database. CAS number: 623-27-8.
Is Terephthalaldehyde used outside cosmetics?
Terephthalaldehyde also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Terephthalaldehyde have different safety status in cosmetics vs industrial chemicals?
Terephthalaldehyde is classified GHS Danger (H302, H311, H315, H319, H331, H335) in the chemicals database but is restricted in EU cosmetics.
Compliance Tools
Check Terephthalaldehyde compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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