NOAEL Data REACH Registered Cosmetic Ingredient

Ammonium nitrate

Also known as: Divosan MH, NH4NO3, Caswell No. 045, EINECS 229-347-8, EPA Pesticide Chemical Code 076101 (+9 more)

CAS 6484-52-2

Ammonium nitrate (CAS 6484-52-2) is a chemical substance. Key regulatory status: REACH registered, 16 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH, ILO ICSC, EPA TRI.

View cosmetic safety profile for Ammonium Nitrate →

Cross-Vertical Regulatory Divergence

Ammonium nitrate is classified GHS Danger (H272, H319, H335) in the chemicals database but is restricted in EU cosmetics.

SOURCE Cross-vertical comparison Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code

SOURCE noael studies public

NOAEL studies

SOURCE chemical inventory jurisdictions

Regulatory lists

SOURCE eu clp annex vi

GHS signal

Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 20 fields

Name

Ammonium nitrate

CAS Number

6484-52-2

DTXSID

DTXSID2029668

Molecular Formula

NO3.H3N

InChI Key

DVARTQFDIMZBAA-UHFFFAOYSA-O

Monoisotopic Mass

79.014367

Synonyms

Divosan MHNH4NO3Caswell No. 045EINECS 229-347-8EPA Pesticide Chemical Code 076101Herco prillsMerco PrillsAmmonium nitricumUNII-T8YA51M7Y6Ammonium saltpeterAmmonium(I) nitrate (1:1)Nitrate of ammonia

ICSC Chemical Safety

International Chemical Safety Card hazard and exposure summary.

SOURCE ILO/WHO International Chemical Safety Cards 1 records

Field	Value
GHS Signal Word	WARNING
GHS Hazard Statements	May intensify fire; oxidizer May be harmful if swallowed Causes skin irritation Causes serious eye irritation May cause damage to blood
Short-term Effects	The substance is irritating to the eyes, skin and respiratory tract. The substance may cause effects on the blood. This may result in the formation of methaemoglobin. The effects may be delayed.
Routes of Exposure	The substance can be absorbed into the body by inhalation and by ingestion.

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 2 records

pH regulating agentOxidizing agent

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 16 records

List	Keyword	Source
active_ingredient; Pesticides	State of California	State of California
active_ingredient; Pesticides	State of California	State of California
active_ingredient; Pesticides	State of California	State of California
active_ingredient; Pesticides	State of California	State of California
active_ingredient; Pesticides	State of California	State of California
active_ingredient; Pesticides	State of California	State of California
active_ingredient; Pesticides	State of California	State of California
active_ingredient; Pesticides	State of California	State of California
active_ingredient; Pesticides	California Department of Pesticide Regulation	State of California
inert_ingredient; Pesticides	EPA	CPCat
inert_ingredient; non_food_use; Pesticides	EPA	CPCat
CEDI	FDA	United States Food and Drug Administration (FDA)
Indirect additives food contact (10/2018)	FDA	United States Food and Drug Administration (FDA)
SCIL (9/2019)	USEPA	Safer Chemical Ingredients List
fracking; water	NY Department of Conservation	CPCat
Canada; consumer_product; Substances in Products - Canada (4/2014)	Government of Canada	CPCat

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 13 of 13 studies

Value	Unit	Endpoint	Route	Species	Source
=36	mg/m3	DNEL systemic	inhalation	Human	ToxValDB_GESTIS_DNEL
18.3	unitless	Draize rabbit irritation score	Ocular	Rabbit	NTP_ICE_eye_irritation
3	unitless	EPA Classification	Ocular	Rabbit	NTP_ICE_eye_irritation
T8YA51M7Y6	UNII	FDA UNII substance identifier	-	-	openFDA substances
T8YA51M7Y6	UNII	FDA UNII substance identifier	-	-	openFDA substances
T8YA51M7Y6	UNII	FDA UNII substance identifier	-	-	openFDA substances
T8YA51M7Y6	UNII	FDA UNII substance identifier	-	-	openFDA substances
2	unitless	GHS Classification	Ocular	Rabbit	NTP_ICE_eye_irritation
2.07	%/sec	Intensity	Ocular	-	NTP_ICE_eye_irritation
=1	mg/L	LOEL	environmental	Mouse	ToxValDB_ECOTOX
-	s	Lag time	Ocular	-	NTP_ICE_eye_irritation
=100	mg/kg bw/day	NOEL	injection	Mouse	ToxValDB_ECOTOX
62	%	Plateau level	Ocular	-	NTP_ICE_eye_irritation

Showing 13 of 13 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records

Status	Name	EC Number	Link
Registered	Ammonium nitrate	229-347-8	ECHA overview →

EPA Toxic Release Inventory (TRI)

TRI hazard and reporting flags for the matched chemical.

SOURCE EPA Toxics Release Inventory (TRI) chemical list 1 records

Chemical	Category	Flags
Ammonium nitrate	N511 - Nitrate compounds (water dissociable; aqueous solution only)	-

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records

Inventory Status

listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB

EU Status

restricted

Max

Pharmaceutical Data

Same-CAS pharmaceutical records from drug and bioactivity sources.

SOURCE EMBL-EBI ChEMBL CHEMBL1500032

ChEMBL Phase

Not listed

Adverse Events

Bioactivity

View full pharmaceutical profile →

Cannabis Data

Same-CAS cannabis compliance and lab records where available.

SOURCE Cannabis regulatory / lab data efsa substances

1 cannabis record found in efsa substances.

View full cannabis profile →

Frequently Asked Questions

What is the NOAEL for Ammonium nitrate?

Ammonium nitrate has 13 NOAEL studies in the database. The lowest reported value is 3 unitless via Ocular in Rabbit. Source: NTP_ICE_eye_irritation.

What regulatory lists include Ammonium nitrate?

Ammonium nitrate appears on 8 regulatory/inventory lists including active_ingredient; Pesticides, inert_ingredient; Pesticides, inert_ingredient; non_food_use; Pesticides, and 5 more. Source: EPA CPDat.

Is Ammonium nitrate used in cosmetics?

Yes, Ammonium nitrate is also indexed as a cosmetic ingredient under the name Ammonium Nitrate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Ammonium nitrate come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, ILO/WHO ICSC, EPA Toxics Release Inventory, CosIng / Ingredients DB, ChEMBL / DailyMed, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.

Does Ammonium nitrate have different safety status in cosmetics vs industrial chemicals?

Ammonium nitrate is classified GHS Danger (H272, H319, H335) in the chemicals database but is restricted in EU cosmetics.

Is Ammonium nitrate used outside industrial chemicals?

Ammonium nitrate also appears in cosmetics, pharmaceutical, cannabis databases.