Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
6 study endpoints found for Ammonium Nitrate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 256 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | >=1500 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | >=1500 mg/kg bw/day | oral | - | oral | REACH |
| NOAEL | 256 mg/kg bw/day | oral | - | oral | REACH |
| NOAEL | 886 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 886 mg/kg bw/day | oral | - | oral | REACH |
GHS Hazard Classification
Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.
Expert Verdict
Explosive precursor with strong oxidizing properties and methemoglobinemia risk; not appropriate for cosmetic formulation due to regulatory restrictions and safety concerns.
Regulatory Flags
Frequently Asked Questions
Is Ammonium Nitrate safe in cosmetics?
Explosive precursor with strong oxidizing properties and methemoglobinemia risk; not appropriate for cosmetic formulation due to regulatory restrictions and safety concerns. The EU classifies Ammonium Nitrate as "restricted". Safety rating: POOR. 6 toxicological study endpoint(s) are available in our database.
Is Ammonium Nitrate allowed in the EU?
Ammonium Nitrate EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.
What does Ammonium Nitrate do in cosmetics?
Ammonium Nitrate functions as: Oxidising agent. It is classified as a cosmetic ingredient in our database. CAS number: 6484-52-2.
What is the Margin of Safety for Ammonium Nitrate?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Ammonium Nitrate?
The NOAEL (No Observed Adverse Effect Level) for Ammonium Nitrate is 256 mg/kg bw/day based on a oral study via oral route in rat. A total of 6 study endpoints are available. Source: REACH.
Is Ammonium Nitrate classified as hazardous under GHS?
Ammonium Nitrate carries a GHS signal word of "WARNING". Hazard statements: May intensify fire; oxidizer May be harmful if swallowed Causes skin irritation Causes serious eye irritation May cause damage to blood. This classification is based on the ILO/WHO International Chemical Safety Card and ECHA C&L inventory data. Note: GHS classification applies to the pure substance — at cosmetic use concentrations, hazard thresholds may not be met.
Compliance Tools
Check Ammonium Nitrate compliance across multiple jurisdictions:
Related Ingredients
Is Ammonium Nitrate in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Ammonium Nitrate in your formulation.