Poor Cosmetic Ingredient GHS Classified

Ammonium Nitrate

INCI: AMMONIUM NITRATE

Ammonium Nitrate (CAS 6484-52-2) is a cosmetic cosmetic ingredient functioning as Oxidising agent. NOAEL 256 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: restricted; GHS signal word WARNING. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.

View industrial chemical safety profile for CAS 6484-52-2 →

Auto-generated CPSR Part A draft with source citations
Function
Oxidising agent
Safety Rating
POOR

Chemistry & Identifiers

EC Number
229-347-8

Regulatory Status

EU EU Status restricted
US US Status restricted
US Notes Regulated as an explosive precursor by ATF/DHS; not appropriate for cosmetic use

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Ammonium Nitrate.

Calculate MoS for your specific formulation with the MoS Calculator.

GHS Hazard Classification

Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.

Signal Word
WARNING
Pictograms
Flam circleExcl markWarnCancerHealth haz
Hazard Statements
May intensify fire; oxidizer May be harmful if swallowed Causes skin irritation Causes serious eye irritation May cause damage to blood
Short-term Exposure Effects
The substance is irritating to the eyes, skin and respiratory tract. The substance may cause effects on the blood. This may result in the formation of methaemoglobin. The effects may be delayed.
Routes of Exposure
The substance can be absorbed into the body by inhalation and by ingestion.

Pre-Calculated Safety Assessment

Pre-calculated NOAEL → SED → MoS audit trail for Ammonium Nitrate across SCCS product categories, with measured dermal absorption where available.

ECHA REACH Registration

European Chemicals Agency REACH dossier and Substances of Very High Concern listing.

Registration Type
Full
Tonnage Band
10,000,000 - 100,000,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Oxidizing agent pH regulating agent
Regulatory List Membership (2)
EPA Safer Chemical Ingredients List (SCIL) FDA Indirect Food Contact Additives

Expert Verdict

Expert safety assessment and concern-level summary for Ammonium Nitrate.

Regulatory Flags

endocrine_disruptor epa_safer_alternative

NOAEL Studies Summary

View details ->

Public NOAEL study rows linked to Ammonium Nitrate by CAS number or substance name.

Studies
12
Lowest NOAEL
256 mg/kg bw/day
Highest NOAEL
1975 mg/kg bw/day
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip

Chemical Function

pH regulating agent Oxidizing agent

Regulatory Lists

active_ingredient; Pesticides active_ingredient; Pesticides active_ingredient; Pesticides active_ingredient; Pesticides active_ingredient; Pesticides active_ingredient; Pesticides active_ingredient; Pesticides active_ingredient; Pesticides active_ingredient; Pesticides inert_ingredient; Pesticides inert_ingredient; non_food_use; Pesticides CEDI Indirect additives food contact (10/2018) SCIL (9/2019) fracking; water Canada; consumer_product; Substances in Products - Canada (4/2014)

Australian Status

AICIS status: listed

Cross-Vertical Safety Context

Same-CAS public records found in pharmaceutical data.

SOURCE ChEMBL / DrugCentral / FAERS DB_PHARMA CAS match

Pharmaceutical Data

Same-CAS rows from the pharmaceutical spoke database.

ChEMBL ID
CHEMBL1500032
View full pharmaceutical profile →

Frequently Asked Questions

Is Ammonium Nitrate safe in cosmetics?

Ammonium Nitrate has a safety rating of "POOR" in our database. EU status: restricted. US status: restricted.

Is Ammonium Nitrate allowed in the EU?

Ammonium Nitrate EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does Ammonium Nitrate do in cosmetics?

Ammonium Nitrate functions as: Oxidising agent. It is classified as a cosmetic ingredient in our database. CAS number: 6484-52-2.

Is Ammonium Nitrate classified as hazardous under GHS?

Ammonium Nitrate carries a GHS signal word of "WARNING". Hazard statements: May intensify fire; oxidizer May be harmful if swallowed Causes skin irritation Causes serious eye irritation May cause damage to blood. This classification is based on the ILO/WHO International Chemical Safety Card and ECHA C&L inventory data. Note: GHS classification applies to the pure substance — at cosmetic use concentrations, hazard thresholds may not be met.

Is Ammonium Nitrate used outside cosmetics?

Ammonium Nitrate also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.

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