What is the NOAEL for Calcium saccharin?
Calcium saccharin has 6 NOAEL studies in the database. The lowest reported value is 5 mg/kg via oral in Human. Source: ToxValDB_WHO_JECFA_ADI.
NOAEL Data
Cosmetic Ingredient
Calcium saccharin
Also known as: 1,2-Benzisothiazol-3(2H)-one, 1,1-dioxide, calcium salt (2:1), Saccharin calcium anhydrous, Calcium o-benzosulfimide, Calcium o-benzosulphimide, Calcium 2-benzosulphimide (+5 more)
CAS 6485-34-3
Calcium saccharin (CAS 6485-34-3) is a chemical substance. Key regulatory status: 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
SOURCE
noael studies public
NOAEL studies
6
SOURCE
chemical inventory jurisdictions
Regulatory lists
1
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
16 fields
Name
Calcium saccharin
CAS Number
6485-34-3
DTXSID
DTXSID0021252
Molecular Formula
2C7H5NO3S.Ca
InChI Key
LNMAXKMUGYXKPJ-UHFFFAOYSA-L
Monoisotopic Mass
405.960619
Synonyms
1,2-Benzisothiazol-3(2H)-one, 1,1-dioxide, calcium salt (2:1)Saccharin calcium anhydrousCalcium o-benzosulfimideCalcium o-benzosulphimideCalcium 2-benzosulphimideCalcium saccharinaCalcium saccharinateEINECS 229-349-9Sulphobenzoic imide calcium saltUNII-09AW1ODN7B
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
2 records
Deodorizer
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
1 records
| List | Keyword | Source |
|---|---|---|
| Indirect additives food contact (10/2018) | FDA | United States Food and Drug Administration (FDA) |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 6 of 6 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| <=5 | mg/kg | ADI | oral | Human | ToxValDB_WHO_JECFA_ADI |
| 09AW1ODN7B | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 09AW1ODN7B | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 09AW1ODN7B | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 09AW1ODN7B | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =200 | mmol/kg | NOEL | oral | Rat | ToxValDB_ECOTOX |
Showing 6 of 6 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
SACCHARIN CALCIUM
ChEMBL Phase
-1
Adverse Events
0
Bioactivity
0
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
1 food-safety record found.
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Calcium saccharin?
Calcium saccharin appears on 1 regulatory/inventory list including Indirect additives food contact (10/2018). Source: EPA CPDat.
Is Calcium saccharin used in cosmetics?
Yes, Calcium saccharin is also indexed as a cosmetic ingredient under the name Calcium Saccharin. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Calcium saccharin come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is Calcium saccharin used outside industrial chemicals?
Calcium saccharin also appears in cosmetics, pharmaceutical, food safety, cannabis databases.