What is the NOAEL for Uracil?
Uracil has 5 NOAEL studies in the database. The lowest reported value is 56HH86ZVCT UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Uracil
Also known as: EINECS 200-621-9, UNII-56HH86ZVCT, 1,2,3,4-tetrahydropyrimidine-2,4-dione, Pirod, Pyrod (+2 more)
CAS 66-22-8
Uracil (CAS 66-22-8) is a chemical substance. Key regulatory status: REACH registered, 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
5
SOURCE
chemical inventory jurisdictions
Regulatory lists
3
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
13 fields
Name
Uracil
CAS Number
66-22-8
DTXSID
DTXSID4021424
Molecular Formula
C4H4N2O2
InChI Key
ISAKRJDGNUQOIC-UHFFFAOYSA-N
Monoisotopic Mass
112.027277
Synonyms
EINECS 200-621-9UNII-56HH86ZVCT1,2,3,4-tetrahydropyrimidine-2,4-dionePirodPyrodUraUrazil
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
1 records
Softener and conditioner
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
3 records
| List | Keyword | Source |
|---|---|---|
| pharmaceutical | US International Trade Commission | CPCat |
| Canada; pharmaceutical | DrugBank | DrugBank |
| Canada; pharmaceutical | DrugBank | DrugBank |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 5 of 5 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 56HH86ZVCT | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 56HH86ZVCT | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 56HH86ZVCT | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 56HH86ZVCT | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| >6000 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
Showing 5 of 5 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Uracil | 200-621-9 | ECHA overview → |
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Skin Conditioning
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
URACIL
ChEMBL Phase
3
Adverse Events
7
Bioactivity
6
Frequently Asked Questions
What regulatory lists include Uracil?
Uracil appears on 2 regulatory/inventory lists including pharmaceutical, Canada; pharmaceutical. Source: EPA CPDat.
Is Uracil used in cosmetics?
Yes, Uracil is also indexed as a cosmetic ingredient under the name Uracil. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Uracil come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Is Uracil used outside industrial chemicals?
Uracil also appears in cosmetics, pharmaceutical databases.