What is the NOAEL for Xanthohumol?
Xanthohumol has 4 NOAEL studies in the database. The lowest reported value is T4467YT1NT UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Xanthohumol
Also known as: 2-Propen-1-one, 1-[2,4-dihydroxy-6-methoxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-, (2E)-, 2-Propen-1-one, 1-[2,4-dihydroxy-6-methoxy-3-(3-methyl-2-butenyl)phenyl]-3-(4-hydroxyphenyl)-, (2E)-, 2-Propen-1-one, 1-[2,4-dihydroxy-6-methoxy-3-(3-methyl-2-butenyl)phenyl]-3-(4-hydroxyphenyl)-, (E)-, (2E)-1-[2,4-Dihydroxy-6-methoxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-2-propen-1-one, Xantho Flav-Pure (+4 more)
CAS 6754-58-1
Xanthohumol (CAS 6754-58-1) is a chemical substance. Key regulatory status: 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat.
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
1
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
15 fields
Name
Xanthohumol
CAS Number
6754-58-1
DTXSID
DTXSID00893171
Molecular Formula
C21H22O5
InChI Key
ORXQGKIUCDPEAJ-YRNVUSSQSA-N
Monoisotopic Mass
354.146724
Synonyms
2-Propen-1-one, 1-[2,4-dihydroxy-6-methoxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-, (2E)-2-Propen-1-one, 1-[2,4-dihydroxy-6-methoxy-3-(3-methyl-2-butenyl)phenyl]-3-(4-hydroxyphenyl)-, (2E)-2-Propen-1-one, 1-[2,4-dihydroxy-6-methoxy-3-(3-methyl-2-butenyl)phenyl]-3-(4-hydroxyphenyl)-, (E)-(2E)-1-[2,4-Dihydroxy-6-methoxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-2-propen-1-oneXantho Flav-PureXantho-FlavEC No.: 614-078-4614-078-4Xanthopure
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
1 records
Softener and conditioner
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
1 records
| List | Keyword | Source |
|---|---|---|
| Canada; pharmaceutical | DrugBank | DrugBank |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| T4467YT1NT | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| T4467YT1NT | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| T4467YT1NT | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| T4467YT1NT | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Skin Conditioning
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
XANTHOHUMOL
ChEMBL Phase
2
Adverse Events
0
Bioactivity
5
Frequently Asked Questions
What regulatory lists include Xanthohumol?
Xanthohumol appears on 1 regulatory/inventory list including Canada; pharmaceutical. Source: EPA CPDat.
Is Xanthohumol used in cosmetics?
Yes, Xanthohumol is also indexed as a cosmetic ingredient under the name Xanthohumol. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Xanthohumol come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Is Xanthohumol used outside industrial chemicals?
Xanthohumol also appears in cosmetics, pharmaceutical databases.