What is the NOAEL for 3-Ethoxy-1,1,5-trimethylcyclohexane?
3-Ethoxy-1,1,5-trimethylcyclohexane has 4 NOAEL studies in the database. The lowest reported value is 0 % via Dermal in Human. Source: NTP_ICE_skin_sensitization.
NOAEL Data
REACH Registered
Cosmetic Ingredient
3-Ethoxy-1,1,5-trimethylcyclohexane
Also known as: Herbavert, Cyclohexane, 3-ethoxy-1,1,5-trimethyl-, Ether, ethyl 3,3,5-trimethylcyclohexyl, 3,3,5-Trimethylcyclohexyl ethyl ether, EINECS 266-722-5 (+1 more)
CAS 67583-77-1
3-Ethoxy-1,1,5-trimethylcyclohexane (CAS 67583-77-1) is a chemical substance. Key regulatory status: REACH registered, 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
View cosmetic safety profile for 3-Ethoxy-1,1,5-Trimethylcyclohexane →
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
1
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
12 fields
Name
3-Ethoxy-1,1,5-trimethylcyclohexane
CAS Number
67583-77-1
DTXSID
DTXSID1052872
Molecular Formula
C11H22O
InChI Key
JVBNHJDWWBSWLE-UHFFFAOYSA-N
Monoisotopic Mass
170.167065
Synonyms
HerbavertCyclohexane, 3-ethoxy-1,1,5-trimethyl-Ether, ethyl 3,3,5-trimethylcyclohexyl3,3,5-Trimethylcyclohexyl ethyl etherEINECS 266-722-5Ethyl 3,3,5-trimethylcyclohexyl ether
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
2 records
Fragrance
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
1 records
| List | Keyword | Source |
|---|---|---|
| IFRA Transparency | IFRA | IFRA |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 1350 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| =500 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
Showing 4 of 4 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 3-ethoxy-1,1,5-trimethylcyclohexane | 266-722-5 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Frequently Asked Questions
What regulatory lists include 3-Ethoxy-1,1,5-trimethylcyclohexane?
3-Ethoxy-1,1,5-trimethylcyclohexane appears on 1 regulatory/inventory list including IFRA Transparency. Source: EPA CPDat.
Is 3-Ethoxy-1,1,5-trimethylcyclohexane used in cosmetics?
Yes, 3-Ethoxy-1,1,5-trimethylcyclohexane is also indexed as a cosmetic ingredient under the name 3-Ethoxy-1,1,5-Trimethylcyclohexane. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 3-Ethoxy-1,1,5-trimethylcyclohexane come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
Is 3-Ethoxy-1,1,5-trimethylcyclohexane used outside industrial chemicals?
3-Ethoxy-1,1,5-trimethylcyclohexane also appears in cosmetics databases.