Good Cosmetic Ingredient NOAEL Data

3-Ethoxy-1,1,5-Trimethylcyclohexane

INCI: 3-ETHOXY-1,1,5-TRIMETHYLCYCLOHEXANE

CAS Number
67583-77-1
Function
Fragrance with herbal character
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted; no specific FDA restriction

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

1 study endpoint found for 3-Ethoxy-1,1,5-Trimethylcyclohexane. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 729 mg/kg bw/day oral rat oral REACH

Expert Verdict

Fragrance ingredient with herbal character; classified as flammable and irritant in laboratory settings but irritation risk is minimal at cosmetic-use concentrations.

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Concern Level: Low

Regulatory Flags

fragrance-component ifra_fragrance

Frequently Asked Questions

Is 3-Ethoxy-1,1,5-Trimethylcyclohexane safe in cosmetics?

Fragrance ingredient with herbal character; classified as flammable and irritant in laboratory settings but irritation risk is minimal at cosmetic-use concentrations. The EU classifies 3-Ethoxy-1,1,5-Trimethylcyclohexane as "permitted". Safety rating: GOOD. 1 toxicological study endpoint(s) are available in our database.

Is 3-Ethoxy-1,1,5-Trimethylcyclohexane allowed in the EU?

3-Ethoxy-1,1,5-Trimethylcyclohexane EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does 3-Ethoxy-1,1,5-Trimethylcyclohexane do in cosmetics?

3-Ethoxy-1,1,5-Trimethylcyclohexane functions as: Fragrance with herbal character. It is classified as a cosmetic ingredient in our database. CAS number: 67583-77-1.

What is the Margin of Safety for 3-Ethoxy-1,1,5-Trimethylcyclohexane?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for 3-Ethoxy-1,1,5-Trimethylcyclohexane?

The NOAEL (No Observed Adverse Effect Level) for 3-Ethoxy-1,1,5-Trimethylcyclohexane is 729 mg/kg bw/day based on a oral study via oral route in rat. Source: REACH.

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