What is the NOAEL for 2-Propen-1-yl 2-(cyclohexyloxy)acetate?
2-Propen-1-yl 2-(cyclohexyloxy)acetate has 13 NOAEL studies in the database. The lowest reported value is 3.34 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
NOAEL Data
REACH Registered
Cosmetic Ingredient
2-Propen-1-yl 2-(cyclohexyloxy)acetate
Also known as: Acetic acid, (cyclohexyloxy)-, 2-propenyl ester, Acetic acid, 2-(cyclohexyloxy)-, 2-propen-1-yl ester, Allyl (cyclohexyloxy)acetate, Allyl cyclohexyloxyacetate, EINECS 272-657-3 (+2 more)
CAS 68901-15-5
2-Propen-1-yl 2-(cyclohexyloxy)acetate (CAS 68901-15-5) is a chemical substance. Key regulatory status: REACH registered, 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
View cosmetic safety profile for cis-3-Hexenyloxyacetaldehyde →
SOURCE
noael studies public
NOAEL studies
13
SOURCE
chemical inventory jurisdictions
Regulatory lists
3
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
13 fields
Name
2-Propen-1-yl 2-(cyclohexyloxy)acetate
CAS Number
68901-15-5
DTXSID
DTXSID1071824
Molecular Formula
C11H18O3
InChI Key
MBUYSYKXSMTIPP-UHFFFAOYSA-N
Monoisotopic Mass
198.125594
Synonyms
Acetic acid, (cyclohexyloxy)-, 2-propenyl esterAcetic acid, 2-(cyclohexyloxy)-, 2-propen-1-yl esterAllyl (cyclohexyloxy)acetateAllyl cyclohexyloxyacetateEINECS 272-657-3CyclogalbanateGalbanum oxyacetate
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
60 records
Fragrance
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
3 records
| List | Keyword | Source |
|---|---|---|
| IFRA Transparency | IFRA | IFRA |
| consumer_product | P&G | Proctor & Gamble |
| Europe; Personal care; restricted | European Commission | CosIng |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 13 of 13 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =3.34 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| B2R58HW644 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| B2R58HW644 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| B2R58HW644 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| B2R58HW644 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =16.1 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =32.2 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =32.8 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =60 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| >=67.6 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| >=75.7 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =20.1 | mg/kg bw/day | NOEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =23.5 | mg/kg bw/day | NOEL | oral | Rat | ToxValDB_ECHA_IUCLID |
Showing 13 of 13 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Allyl (cyclohexyloxy)acetate | 272-657-3 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Frequently Asked Questions
What regulatory lists include 2-Propen-1-yl 2-(cyclohexyloxy)acetate?
2-Propen-1-yl 2-(cyclohexyloxy)acetate appears on 3 regulatory/inventory lists including IFRA Transparency, consumer_product, Europe; Personal care; restricted. Source: EPA CPDat.
Is 2-Propen-1-yl 2-(cyclohexyloxy)acetate used in cosmetics?
Yes, 2-Propen-1-yl 2-(cyclohexyloxy)acetate is also indexed as a cosmetic ingredient under the name cis-3-Hexenyloxyacetaldehyde. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 2-Propen-1-yl 2-(cyclohexyloxy)acetate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
Is 2-Propen-1-yl 2-(cyclohexyloxy)acetate used outside industrial chemicals?
2-Propen-1-yl 2-(cyclohexyloxy)acetate also appears in cosmetics databases.