What is the NOAEL for Dodecanedioic acid?
Dodecanedioic acid has 5 NOAEL studies in the database. The lowest reported value is 127 mg/m3 via inhalation in Human. Source: ToxValDB GESTIS DNEL.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Dodecanedioic acid
Also known as: EINECS 211-746-3, UNII-978YU42Q6I, 1,10-Decanedicarboxylate, 1,12-Dodecanedioate, Decamethylenedicarboxylate (+5 more)
CAS 693-23-2
Dodecanedioic acid (CAS 693-23-2) is a chemical substance. Key regulatory status: REACH registered, 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
SOURCE
NOAEL studies
NOAEL studies
5
SOURCE
Chemical inventory jurisdictions
Regulatory lists
2
SOURCE
EU CLP Annex VI
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
15 fields
Name
Dodecanedioic acid
CAS Number
693-23-2
Molecular Formula
C12H22O4
InChI Key
TVIDDXQYHWJXFK-UHFFFAOYSA-N
Monoisotopic Mass
230.151809
Synonyms
EINECS 211-746-3UNII-978YU42Q6I1,10-Decanedicarboxylate1,12-DodecanedioateDecamethylenedicarboxylateDodecanedioateN-Dodecane-a,w-dioateN-Dodecane-a,w-dioic acidN-DodecanedioateSL-AH
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
7 records
Softener and conditionerCorrosion inhibitorChemical reaction regulatorFlow promoter
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
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EPA CPDat
2 records
| List | Keyword | Source |
|---|---|---|
| CEDI | FDA | United States Food and Drug Administration (FDA) |
| Indirect additives food contact (10/2018) | FDA | United States Food and Drug Administration (FDA) |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 5 of 5 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =127 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB GESTIS DNEL |
| 978YU42Q6I | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =1000 | mg/kg bw/day | NOAEL | oral | Rat | ECHA |
| =1800 | mg/kg bw/day | NOAEL | oral | Rat | ECHA |
| =2400 | mg/kg bw/day | NOAEL | oral | Rat | ECHA |
Showing 5 of 5 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Dodecanedioic acid | 211-746-3 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
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AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
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CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Skin Conditioning
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
ChEMBL / DailyMed
CHEMBL3182356
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Frequently Asked Questions
What regulatory lists include Dodecanedioic acid?
Dodecanedioic acid appears on 2 regulatory/inventory lists including CEDI, Indirect additives food contact (10/2018). Source: EPA CPDat.
Is Dodecanedioic acid used in cosmetics?
Yes, Dodecanedioic acid is also indexed as a cosmetic ingredient under the name Dodecanedioic Acid. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Dodecanedioic acid come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Is Dodecanedioic acid used outside industrial chemicals?
Dodecanedioic acid also appears in cosmetics, pharmaceutical databases.