Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
3 study endpoints found for Dodecanedioic Acid. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 1800 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 2400 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 1000 mg/kg bw/day | oral | rat | oral | REACH |
Expert Verdict
Mild skin and eye irritant (H315, H319); no carcinogenic, mutagenic, or reprotoxic effects; standard handling precautions recommended.
Frequently Asked Questions
Is Dodecanedioic Acid safe in cosmetics?
Mild skin and eye irritant (H315, H319); no carcinogenic, mutagenic, or reprotoxic effects; standard handling precautions recommended. The EU classifies Dodecanedioic Acid as "permitted". Safety rating: GOOD. 3 toxicological study endpoint(s) are available in our database.
Is Dodecanedioic Acid allowed in the EU?
Dodecanedioic Acid EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Dodecanedioic Acid do in cosmetics?
Dodecanedioic Acid functions as: Skin conditioning agent; pH adjuster; monomer for polymer synthesis. It is classified as a cosmetic ingredient in our database. CAS number: 693-23-2.
What is the Margin of Safety for Dodecanedioic Acid?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Dodecanedioic Acid?
The NOAEL (No Observed Adverse Effect Level) for Dodecanedioic Acid is 1800 mg/kg bw/day based on a oral study via oral route in rat. A total of 3 study endpoints are available. Source: REACH.
Compliance Tools
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Related Ingredients
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