NOAEL Data Cosmetic Ingredient

3-Amino-2,6-dimethylphenol

Also known as: EINECS 230-268-6, UNII-KK52J0MQ7D

CAS 6994-64-5

3-Amino-2,6-dimethylphenol (CAS 6994-64-5) is a chemical substance. Key regulatory status: 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, SCCS.

View cosmetic safety profile for 3-Amino-2,6-Dimethylphenol →

SOURCE NOAEL studies

NOAEL studies

SOURCE Chemical inventory jurisdictions

Regulatory lists

SOURCE EU CLP Annex VI

GHS signal

Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 7 fields

Name

3-Amino-2,6-dimethylphenol

CAS Number

6994-64-5

Molecular Formula

C8H11NO

InChI Key

XSBKXUJEVYHSNO-UHFFFAOYSA-N

Monoisotopic Mass

137.084064

Synonyms

EINECS 230-268-6UNII-KK52J0MQ7D

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 2 records

Dye

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 1 records

List	Keyword	Source
Europe; Personal care; restricted	European Commission	CosIng

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 16 of 16 studies

Value	Unit	Endpoint	Route	Species	Source
150	mg/kg bw/day	-	-	-	Regulatory source
150	mg/kg bw/day	-	-	human	Regulatory source
KK52J0MQ7D	UNII	FDA UNII substance identifier	-	-	openFDA substances
=0.08	mg/kg bw	NOAEL	dermal	rat	SCCS Opinion
=60	mg/kg bw/d	NOAEL	dermal	rat	SCCS Opinion
=60	mg/kg bw/day	NOAEL	oral	rat	SCCS Opinion
=70	mg/kg bw/day	NOAEL	-	rat	SCCS Opinion
=150	mg/kg bw/day	NOAEL	-	-	SCCS Opinion
=2000	mg/kg bw	NOAEL	oral	rat	SCCS Opinion
=0.08	mg/kg bw	developmental toxicity	dermal	rat	Regulatory source
=60	mg/kg bw/d	developmental toxicity	dermal	rat	Regulatory source
=60	mg/kg bw/d	developmental toxicity	oral	rat	Regulatory source
70	mg/kg bw/day	genotoxicity	-	rat	Regulatory source
60	mg/kg bw/day	reproductive toxicity	oral	rat	Regulatory source
70	mg/kg bw/day	reproductive toxicity	oral	rat	Regulatory source
2000	mg/kg bw	reproductive toxicity	oral	rat	Regulatory source

Showing 16 of 16 studies

SCCS Opinions

EU Scientific Committee opinions tied to the matched substance.

SOURCE SCCS Opinion 1 opinions

Opinion	Date	Conclusion	Max Conc.	Concerns
SCCS/1529/14	18 June 2014	safe	2.0%	sensitisation potential not excluded

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB

EU Status

restricted

Max

Frequently Asked Questions

What is the NOAEL for 3-Amino-2,6-dimethylphenol?

3-Amino-2,6-dimethylphenol has 16 NOAEL studies in the database. The lowest reported value is 150 mg/kg bw/day. Source: Regulatory source.

What regulatory lists include 3-Amino-2,6-dimethylphenol?

3-Amino-2,6-dimethylphenol appears on 1 regulatory/inventory list including Europe; Personal care; restricted. Source: EPA CPDat.

Is 3-Amino-2,6-dimethylphenol used in cosmetics?

Yes, 3-Amino-2,6-dimethylphenol is also indexed as a cosmetic ingredient under the name 3-Amino-2,6-Dimethylphenol. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for 3-Amino-2,6-dimethylphenol come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.

Is 3-Amino-2,6-dimethylphenol used outside industrial chemicals?

3-Amino-2,6-dimethylphenol also appears in cosmetics databases.