NOAEL Data REACH Registered Cosmetic Ingredient

Ethanol, 2-​(2,​4-​diaminophenoxy)​-​, sulfate (1:1)

CAS 70643-20-8

Ethanol, 2-​(2,​4-​diaminophenoxy)​-​, sulfate (1:1) (CAS 70643-20-8) is a chemical substance. Key regulatory status: REACH registered, 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.

View cosmetic safety profile for 2,4-Diaminophenoxyethanol Sulfate →

SOURCE noael studies public
NOAEL studies
4
SOURCE chemical inventory jurisdictions
Regulatory lists
1
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 6 fields
Name
Ethanol, 2-​(2,​4-​diaminophenoxy)​-​, sulfate (1:1)
CAS Number
70643-20-8
DTXSID
DTXSID70892454
Molecular Formula
C8H12N2O2.H2O4S
InChI Key
UUHBEKCQQLDQNG-UHFFFAOYSA-N
Monoisotopic Mass
266.057257

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 4 records
Dye

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 1 records
ListKeywordSource
Europe; Personal care - hair coloringDanish Environmental Protection AgencyDanish EPA

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 4 of 4 studies
ValueUnitEndpointRouteSpeciesSource
671N06DARLUNIIFDA UNII substance identifier--openFDA substances
671N06DARLUNIIFDA UNII substance identifier--openFDA substances
671N06DARLUNIIFDA UNII substance identifier--openFDA substances
671N06DARLUNIIFDA UNII substance identifier--openFDA substances

Showing 4 of 4 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA (EU) 1 records
StatusNameEC NumberLink
Registered[4-(2-hydroxyethoxy)-1,3-phenylene]diammonium sulphate274-713-2ECHA overview →

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed_with_terms
Conditions
Specific information requirements: Obligations to provide information apply. These obligations are: 1. A person introducing this chemical must tell us in writing within 28 calendar days if any of the following circumstances have occurred in relation to their introduction (importation or manufacture): a. the introduction volume of the chemical exceeds 1 tonne per annum b. the chemical is imported in solid form c. the chemical is imported for formulation in Australia d. the concentration in hair dye products has increased from 4% e. the chemical has begun to be formulated into products in Australia f. additional information becomes available to the person as to the adverse effects of the oxidative reaction products created during hair dye use 2. A person who introduces this chemical must tell us in writing within 28 calendar days if they become aware of any of the following circumstances, namely, that since the assessment under the Industrial Chemicals (Notification and Assessment) Act 1989: a. the function or use of the chemical has changed, or is likely to change, significantly; b. the amount of the chemical being introduced has increased, or is likely to increase, significantly; c. in the case of a chemical not manufactured, or proposed to be manufactured, in Australia at the time of the assessment—it has begun to be manufactured in Australia; d. the method of manufacture of the chemical in Australia has changed, or is likely to change, in a way that may result in an increased risk of an adverse effect of the chemical on occupational health and safety, public health or the environment; e. additional information has become available to the person as to an adverse effect of the chemical on occupational health and safety, public health or the environment.

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
restricted
Max
2.0%
Category
Colorant
View full cosmetic safety profile →

Frequently Asked Questions

What is the NOAEL for Ethanol, 2-​(2,​4-​diaminophenoxy)​-​, sulfate (1:1)?

Ethanol, 2-​(2,​4-​diaminophenoxy)​-​, sulfate (1:1) has 4 NOAEL studies in the database. The lowest reported value is 671N06DARL UNII. Source: openFDA substances.

What regulatory lists include Ethanol, 2-​(2,​4-​diaminophenoxy)​-​, sulfate (1:1)?

Ethanol, 2-​(2,​4-​diaminophenoxy)​-​, sulfate (1:1) appears on 1 regulatory/inventory list including Europe; Personal care - hair coloring. Source: EPA CPDat.

Is Ethanol, 2-​(2,​4-​diaminophenoxy)​-​, sulfate (1:1) used in cosmetics?

Yes, Ethanol, 2-​(2,​4-​diaminophenoxy)​-​, sulfate (1:1) is also indexed as a cosmetic ingredient under the name 2,4-Diaminophenoxyethanol Sulfate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Ethanol, 2-​(2,​4-​diaminophenoxy)​-​, sulfate (1:1) come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.

Does Ethanol, 2-​(2,​4-​diaminophenoxy)​-​, sulfate (1:1) have different safety status in cosmetics vs industrial chemicals?

Ethanol, 2-​(2,​4-​diaminophenoxy)​-​, sulfate (1:1) is classified GHS Danger (H302, H317, H318, H319, H411, H315, H335) in the chemicals database but is restricted in EU cosmetics at max 2.0%.

Is Ethanol, 2-​(2,​4-​diaminophenoxy)​-​, sulfate (1:1) used outside industrial chemicals?

Ethanol, 2-​(2,​4-​diaminophenoxy)​-​, sulfate (1:1) also appears in cosmetics databases.