Also known as: BBOT, 2,5-Bis(5-tert-butylbenzoxazol-2-yl)thiophene, Benzoxazole, 2,2'-(2,5-thiophenediyl)bis[5-(1,1-dimethylethyl)-, Benzoxazole, 2,2'-(2,5-thiophenediyl)bis[5-tert-butyl-, 2,2'-(2,5-Thiophenediyl)bis[5-tert-butylbenzoxazole] (+15 more)
CAS 7128-64-5
2,2'-(2,5-Thiophenediyl)bis[5-(1,1-dimethylethyl)benzoxazole] (CAS 7128-64-5) is a chemical substance. Key regulatory status: REACH registered, 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
View cosmetic safety profile for BIS(T-BUTYL BENZOXAZOLYL) THIOPHENE →
CAS, identifiers, formula, and alternate names for the matched substance record.
Industrial and product-use categories associated with this substance.
Inventory, screening, and regulatory list matches from public chemical databases.
| List | Keyword | Source |
|---|---|---|
| Indirect additives food contact (10/2018) | FDA | United States Food and Drug Administration (FDA) |
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
| drinking_water; Europe; manufacturing; plastic_additive | Belgaqua | CPCat |
Toxicology endpoints rendered from public NOAEL study rows.
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =3 | mg/m3 | DNEL local | inhalation | Human | ToxValDB GESTIS DNEL |
| W7UR9129GP | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| W7UR9129GP | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| W7UR9129GP | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| W7UR9129GP | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| >10000 | mg/kg bw | LD50 | oral | Rat | NTP ICE acute oral |
| 3000 | ppm | LOAEL | oral | rat | COSMOS DB |
| 1000 | ppm | NOAEL | oral | rat | COSMOS DB |
| =2500 | mg/kg bw/day | NOAEL | oral | Dog | ECHA |
| 5000 | ppm | NOAEL | oral | dog | COSMOS DB |
| =7800 | mg/kg bw/day | NOAEL | oral | Rat | ECHA |
| =78 | mg/kg bw/day | NOEL | oral | Rat | ECHA |
| =185 | mg/kg bw/day | NOEL | oral | Mouse | ECHA |
| =1000 | ppm | NOEL | oral | Mouse | ECHA |
| =1571 | mg/kg bw/day | NOEL | oral | Dog | ECHA |
| =1682 | mg/kg bw/day | NOEL | oral | Dog | ECHA |
Showing 16 of 16 studies
Registration status from the ECHA REACH registered substances database.
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 2,5-thiophenediylbis(5-tert-butyl-1,3-benzoxazole) | 230-426-4 | ECHA overview → |
Australian industrial chemicals inventory status and applicable conditions.
Same-CAS cosmetic ingredient record for cross-vertical context.
2,2'-(2,5-Thiophenediyl)bis[5-(1,1-dimethylethyl)benzoxazole] has 16 NOAEL studies in the database. The lowest reported value is 3 mg/m3 via inhalation in Human. Source: ToxValDB GESTIS DNEL.
2,2'-(2,5-Thiophenediyl)bis[5-(1,1-dimethylethyl)benzoxazole] appears on 3 regulatory/inventory lists including Indirect additives food contact (10/2018), inert_ingredient; non_food_use; Pesticides, drinking_water; Europe; manufacturing; plastic_additive. Source: EPA CPDat.
Yes, 2,2'-(2,5-Thiophenediyl)bis[5-(1,1-dimethylethyl)benzoxazole] is also indexed as a cosmetic ingredient under the name BIS(T-BUTYL BENZOXAZOLYL) THIOPHENE. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
2,2'-(2,5-Thiophenediyl)bis[5-(1,1-dimethylethyl)benzoxazole] also appears in cosmetics databases.