Good Cosmetic Ingredient NOAEL Data

BIS(T-BUTYL BENZOXAZOLYL) THIOPHENE

CAS Number
7128-64-5
Function
Skin Conditioning
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status Permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status Not specifically regulated

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Toxicological Studies

4 study endpoints found for BIS(T-BUTYL BENZOXAZOLYL) THIOPHENE. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 5000 ppm oral dog Subchronic COSMOS_DB
LOAEL 50000 ppm oral dog Subchronic COSMOS_DB
NOAEL 1000 ppm oral rat Subchronic COSMOS_DB
LOAEL 3000 ppm oral rat Subchronic COSMOS_DB

Expert Verdict

BIS(T-BUTYL BENZOXAZOLYL) THIOPHENE is listed in the EU CosIng database with functions: Skin Conditioning It is permitted in the EU without specific restrictions.

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Concern Level: Low

Regulatory Flags

cosing-sourced eu-permitted skin-conditioning needs-enrichment

Frequently Asked Questions

Is BIS(T-BUTYL BENZOXAZOLYL) THIOPHENE safe in cosmetics?

BIS(T-BUTYL BENZOXAZOLYL) THIOPHENE is listed in the EU CosIng database with functions: Skin Conditioning It is permitted in the EU without specific restrictions. The EU classifies BIS(T-BUTYL BENZOXAZOLYL) THIOPHENE as "Permitted". Safety rating: GOOD. 4 toxicological study endpoint(s) are available in our database.

Is BIS(T-BUTYL BENZOXAZOLYL) THIOPHENE allowed in the EU?

BIS(T-BUTYL BENZOXAZOLYL) THIOPHENE EU regulatory status: Permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does BIS(T-BUTYL BENZOXAZOLYL) THIOPHENE do in cosmetics?

BIS(T-BUTYL BENZOXAZOLYL) THIOPHENE functions as: Skin Conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 7128-64-5.

What is the NOAEL for BIS(T-BUTYL BENZOXAZOLYL) THIOPHENE?

The NOAEL (No Observed Adverse Effect Level) for BIS(T-BUTYL BENZOXAZOLYL) THIOPHENE is 5000 ppm based on a Subchronic study via oral route in dog. A total of 4 study endpoints are available. Source: COSMOS_DB.

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