Danger GHS07GHS05 NOAEL Data REACH Registered Cosmetic Ingredient

Didecyldimethylammonium chloride

Also known as: Didecyl dimethyl ammonium chloride (1-Decanaminium, N-decyl-N,N-dimethyl-, chloride) (DDAC), AMMONIUM CHLORIDE, N,N-DIDECYL-N,N-DIMETHYL-, DDAC C10-C10, Aliquat 203, Bio-dac 50-22 (+7 more)

CAS 7173-51-5

Didecyldimethylammonium chloride (CAS 7173-51-5) is a chemical substance with GHS signal word Danger; key hazard signal: H302; H314. Key regulatory status: REACH registered, 36 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from ECHA CLP, EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.

View cosmetic safety profile for Didecyldimonium Chloride →

Cross-Vertical Regulatory Divergence

Didecyldimethylammonium chloride is classified GHS Danger (H302, H314) in the chemicals database but is allowed in EU cosmetics.

SOURCE Cross-vertical comparison Cosmetics: ingredients.eu_status; Chemicals: eu_clp_annex_vi.signal_word/hazard_statement_code

SOURCE NOAEL studies

NOAEL studies

100

SOURCE Chemical inventory jurisdictions

Regulatory lists

SOURCE EU CLP Annex VI

GHS signal

Danger

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 18 fields

Name

Didecyldimethylammonium chloride

CAS Number

7173-51-5

DTXSID

DTXSID9032537

Molecular Formula

C22H48N.ClH

InChI Key

RUPBZQFQVRMKDG-UHFFFAOYSA-M

Monoisotopic Mass

362.355353

Synonyms

Didecyl dimethyl ammonium chloride (1-Decanaminium, N-decyl-N,N-dimethyl-, chloride) (DDAC)AMMONIUM CHLORIDE, N,N-DIDECYL-N,N-DIMETHYL-DDAC C10-C10Aliquat 203Bio-dac 50-22Caswell No. 331AEINECS 230-525-2EPA Pesticide Chemical Code 069149Quaternium-12UNII-JXN40O9Y9BDairyland brand chg teat dipN-Decyl-N,N-dimethyl-1-decanaminium chloride

GHS / CLP Classification

EU harmonized hazard classification, hazard statements, pictograms, and signal word.

SOURCE EU CLP Annex VI (ECHA) 1 classifications

Hazard Class	H-Statements	Pictograms	Signal
Acute Tox. 4 *; Skin Corr. 1B	H302; H314	GHS07; GHS05	Danger

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 60 records

Surfactant (surface active agent)BiocideAnti-static agentEmulsifierSoftener and conditionerFragrance

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 36 records

List	Keyword	Source
inert_ingredient; non_food_use; Pesticides	EPA	CPCat
active_ingredient; Pesticides	State of California	State of California
active_ingredient; Pesticides	State of California	State of California
active_ingredient; Pesticides	State of California	State of California
active_ingredient; Pesticides	State of California	State of California
active_ingredient; Pesticides	State of California	State of California
active_ingredient; Pesticides	State of California	State of California
active_ingredient; Pesticides	State of California	State of California
active_ingredient; Pesticides	State of California	State of California
active_ingredient; Pesticides	State of California	State of California
active_ingredient; Pesticides	State of California	State of California
active_ingredient; Pesticides	State of California	State of California
active_ingredient; Pesticides	State of California	State of California
active_ingredient; Pesticides	State of California	State of California
active_ingredient; Pesticides	State of California	State of California
active_ingredient; Pesticides	State of California	State of California
active_ingredient; Pesticides	State of California	State of California
active_ingredient; Pesticides	State of California	State of California
active_ingredient; Pesticides	California Department of Pesticide Regulation	State of California
active_ingredient; Pesticides	MN Department of Agriculture Pesticide Sales Database	CPCat
active_ingredient; Pesticides	MN Department of Agriculture Pesticide Sales Database	CPCat
active_ingredient; Pesticides	MN Department of Agriculture Pesticide Sales Database	CPCat
active_ingredient; Pesticides	MN Department of Agriculture Pesticide Sales Database	CPCat
active_ingredient; Pesticides	MN Department of Agriculture Pesticide Sales Database	CPCat
active_ingredient; Pesticides	MN Department of Agriculture Pesticide Sales Database	CPCat
active_ingredient; Pesticides	MN Department of Agriculture Pesticide Sales Database	CPCat
active_ingredient; Pesticides	MN Department of Agriculture Pesticide Sales Database	CPCat
active_ingredient; Pesticides	MN Department of Agriculture Pesticide Sales Database	CPCat
active_ingredient; Pesticides	MN Department of Agriculture Pesticide Sales Database	CPCat
active_ingredient; Pesticides	MN Department of Agriculture Pesticide Sales Database	CPCat
active_ingredient; Pesticides	MN Department of Agriculture Pesticide Sales Database	CPCat
active_ingredient; Europe; Pesticides	European Commission	CPCat
CEDI	FDA	United States Food and Drug Administration (FDA)
Indirect additives food contact (10/2018)	FDA	United States Food and Drug Administration (FDA)
active_ingredient; Europe; Pesticides	Commission of the European Communities	CPCat
IFRA Transparency	IFRA	IFRA

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 50 of 100 studies

Value	Unit	Endpoint	Route	Species	Source
8.77563586952748	uM	AC50	-	-	NTP ICE endocrine
19.0571698882926	uM	AC50	-	-	NTP ICE endocrine
8.30535999448496	uM	ACC	-	-	NTP ICE endocrine
12.2235650081618	uM	ACC	-	-	NTP ICE endocrine
18.65	uL/min/10^6 cells	Clint	-	Human	NTP ICE adme parameters
2	unitless	EPA Classification	Ocular	Rabbit	NTP ICE eye irritation
2	unitless	EPA Classification	Ocular	Rabbit	NTP ICE eye irritation
2	unitless	EPA Classification	Ocular	Rabbit	NTP ICE eye irritation
2	unitless	EPA Classification	Ocular	Rabbit	NTP ICE eye irritation
3	unitless	EPA Classification	Ocular	Rabbit	NTP ICE eye irritation
3	unitless	EPA Classification	Ocular	Rabbit	NTP ICE eye irritation
3	unitless	EPA Classification	Ocular	Rabbit	NTP ICE eye irritation
3	unitless	EPA Classification	Ocular	Rabbit	NTP ICE eye irritation
4	unitless	EPA Classification	Inhalation	-	NTP ICE acute inhalation
4	unitless	EPA Classification	Ocular	Rabbit	NTP ICE eye irritation
4	unitless	EPA Classification	Ocular	Rabbit	NTP ICE eye irritation
4	unitless	EPA Classification	Ocular	Rabbit	NTP ICE eye irritation
4	unitless	EPA Classification	Ocular	Rabbit	NTP ICE eye irritation
1	unitless	EPA classification	Dermal	Rabbit	NTP ICE skin irritation
1	unitless	EPA classification	Dermal	Rabbit	NTP ICE skin irritation
2	unitless	EPA classification	Dermal	Rabbit	NTP ICE skin irritation
2	unitless	EPA classification	Dermal	Rabbit	NTP ICE skin irritation
=3	Unitless	EPA classification	oral	Rat (Female)	NTP ICE acute oral
4	unitless	EPA classification	Dermal	Rat	NTP ICE acute dermal
=4	Unitless	EPA classification	oral	Rat (Female)	NTP ICE acute oral
=4	Unitless	EPA classification	oral	Rat (Female)	NTP ICE acute oral
=4	Unitless	EPA classification	oral	Rat (Female)	NTP ICE acute oral
=4	Unitless	EPA classification	oral	Rat	NTP ICE acute oral
4	unitless	EPA classification	Dermal	Rabbit	NTP ICE skin irritation
4	unitless	EPA classification	Dermal	Rabbit	NTP ICE skin irritation
JXN40O9Y9B	UNII	FDA UNII substance identifier	-	-	openFDA substances
JXN40O9Y9B	UNII	FDA UNII substance identifier	-	-	openFDA substances
JXN40O9Y9B	UNII	FDA UNII substance identifier	-	-	openFDA substances
JXN40O9Y9B	UNII	FDA UNII substance identifier	-	-	openFDA substances
-	fraction	Fu	-	Human	NTP ICE adme parameters
1	unitless	GHS Classification	Dermal	Mouse	NTP ICE skin sensitization
1	unitless	GHS Classification	Dermal	Mouse	NTP ICE skin sensitization
1	unitless	GHS Classification	Dermal	Mouse	NTP ICE skin sensitization
1	unitless	GHS Classification	Dermal	Mouse	NTP ICE skin sensitization
5	unitless	GHS Classification	Inhalation	-	NTP ICE acute inhalation
=4	Unitless	GHS classification	oral	Rat (Female)	NTP ICE acute oral
5	unitless	GHS classification	Dermal	Rat	NTP ICE acute dermal
=5	Unitless	GHS classification	oral	Rat (Female)	NTP ICE acute oral
=5	Unitless	GHS classification	oral	Rat	NTP ICE acute oral
=5	Unitless	GHS classification	oral	Rat (Female)	NTP ICE acute oral
=5	Unitless	GHS classification	oral	Rat (Female)	NTP ICE acute oral
range0.052	mg/L	LC50	Inhalation	-	NTP ICE acute inhalation
>2.02	mg/L	LC50	Inhalation	-	NTP ICE acute inhalation
>2.16	mg/L	LC50	Inhalation	-	NTP ICE acute inhalation
>5.06	mg/L	LC50	Inhalation	-	NTP ICE acute inhalation

Showing 50 of 100 studies

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA 1 records

Status	Name	EC Number	Link
Registered	Didecyldimethylammonium chloride	230-525-2	ECHA overview →

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records

Inventory Status

listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB

EU Status

permitted

Max

Pharmaceutical Data

Same-CAS pharmaceutical records from drug and bioactivity sources.

SOURCE ChEMBL / DailyMed DIDECYLDIMETHYLAMMONIUM CHLORIDE

ChEMBL Phase

-1

Adverse Events

Bioactivity

View full pharmaceutical profile →

Frequently Asked Questions

What is the GHS hazard classification for Didecyldimethylammonium chloride?

Didecyldimethylammonium chloride (CAS 7173-51-5) is classified under EU CLP Annex VI as Acute Tox. 4 *; Skin Corr. 1B with signal word Danger. Hazard statements: H302; H314. Source: EU CLP Annex VI (ECHA).

What is the NOAEL for Didecyldimethylammonium chloride?

Didecyldimethylammonium chloride has 100 NOAEL studies in the database. The lowest reported value is 0 fraction in Human. Source: NTP ICE adme parameters.

What regulatory lists include Didecyldimethylammonium chloride?

Didecyldimethylammonium chloride appears on 6 regulatory/inventory lists including inert_ingredient; non_food_use; Pesticides, active_ingredient; Pesticides, active_ingredient; Europe; Pesticides, and 3 more. Source: EPA CPDat.

Is Didecyldimethylammonium chloride used in cosmetics?

Yes, Didecyldimethylammonium chloride is also indexed as a cosmetic ingredient under the name Didecyldimonium Chloride. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Didecyldimethylammonium chloride come from?

Safety data is sourced from ECHA CLP Annex VI, EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.

Does Didecyldimethylammonium chloride have different safety status in cosmetics vs industrial chemicals?

Didecyldimethylammonium chloride is classified GHS Danger (H302, H314) in the chemicals database but is allowed in EU cosmetics.

Is Didecyldimethylammonium chloride used outside industrial chemicals?

Didecyldimethylammonium chloride also appears in cosmetics, pharmaceutical databases.