REACH Registered Cosmetic Ingredient

L-Tryptophan

Also known as: (S)-2-Amino-3-(1H-indol-3-yl)propanoic acid, Triptophan, L-TRYPTOPHAN (AMINO ACID), Alanine, 3-indol-3-yl-, L-alpha-Aminoindole-3-propionic acid (+15 more)

CAS 73-22-3

L-Tryptophan (CAS 73-22-3) is a chemical substance. Key regulatory status: REACH registered, 4 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA CPDat, ECHA REACH.

View cosmetic safety profile for L-Tryptophan →

SOURCE NOAEL studies

NOAEL studies

SOURCE Chemical inventory jurisdictions

Regulatory lists

SOURCE EU CLP Annex VI

GHS signal

Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 25 fields

Name

L-Tryptophan

CAS Number

73-22-3

Molecular Formula

C11H12N2O2

InChI Key

QIVBCDIJIAJPQS-VIFPVBQESA-N

Monoisotopic Mass

204.089878

Synonyms

(S)-2-Amino-3-(1H-indol-3-yl)propanoic acidTriptophanL-TRYPTOPHAN (AMINO ACID)Alanine, 3-indol-3-yl-L-alpha-Aminoindole-3-propionic acidalpha'-Amino-3-indolepropionic acidalpha-Amino-3-indolepropionic acid, L-EINECS 200-795-61H-Indole-3-propanoic acid, alpha-amino-, (S)-Indole-3-propionic acid, alpha-amino-NCI-C01729Propionic acid, 2-amino-3-indol-3-yl-

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 1 records

Flavouring and nutrient

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 4 records

List	Keyword	Source
active_ingredient; Europe; Pesticides	European Commission	CPCat
inert_ingredient; Pesticides	EPA	CPCat
inert_ingredient; non_food_use; Pesticides	EPA	CPCat
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)	FDA	United States Food and Drug Administration (FDA)

REACH Registration

Registration status from the ECHA REACH registered substances database.

SOURCE ECHA 1 records

Status	Name	EC Number	Link
Registered	L-tryptophan	200-795-6	ECHA overview →

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB

EU Status

permitted

Max

Pharmaceutical Data

Same-CAS pharmaceutical records from drug and bioactivity sources.

SOURCE ChEMBL / DailyMed TRYPTOPHAN

ChEMBL Phase

Adverse Events

Bioactivity

View full pharmaceutical profile →

Cannabis Data

Same-CAS cannabis compliance and lab records where available.

SOURCE Cannabis regulatory / lab data efsa substances

1 cannabis record found in efsa substances.

View full cannabis profile →

Frequently Asked Questions

What regulatory lists include L-Tryptophan?

L-Tryptophan appears on 4 regulatory/inventory lists including active_ingredient; Europe; Pesticides, inert_ingredient; Pesticides, inert_ingredient; non_food_use; Pesticides, and 1 more. Source: EPA CPDat.

Is L-Tryptophan used in cosmetics?

Yes, L-Tryptophan is also indexed as a cosmetic ingredient under the name L-Tryptophan. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for L-Tryptophan come from?

Safety data is sourced from EPA CPDat, EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.

Is L-Tryptophan used outside industrial chemicals?

L-Tryptophan also appears in cosmetics, pharmaceutical, cannabis databases.