What is the NOAEL for Adenine?
Adenine has 7 NOAEL studies in the database. The lowest reported value is JAC85A2161 UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Adenine
Also known as: Vitamin B4 (adenine), EINECS 200-796-1, 1H-Purine, 6-amino, Purine, 6-amino-, 9H-Purine, 1,6-dihydro-6-imino- (+10 more)
CAS 73-24-5
Adenine (CAS 73-24-5) is a chemical substance. Key regulatory status: REACH registered, 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, ECHA REACH.
Cross-Vertical Regulatory Divergence
Adenine is classified GHS Danger (H301) in the chemicals database but is allowed in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
7
SOURCE
chemical inventory jurisdictions
Regulatory lists
3
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
21 fields
Name
Adenine
CAS Number
73-24-5
DTXSID
DTXSID6022557
Molecular Formula
C5H5N5
InChI Key
GFFGJBXGBJISGV-UHFFFAOYSA-N
Monoisotopic Mass
135.054495
Synonyms
Vitamin B4 (adenine)EINECS 200-796-11H-Purine, 6-aminoPurine, 6-amino-9H-Purine, 1,6-dihydro-6-imino-UNII-JAC85A21611H-Purine-6-amine6-Amino-7H-purine6-Amino-Purine9H-Purin-6-yl-amin9H-Purin-6-ylamine9H-Purine-6-amine
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
1 records
Softener and conditioner
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
3 records
| List | Keyword | Source |
|---|---|---|
| Canada; pharmaceutical | DrugBank | DrugBank |
| Canada; pharmaceutical | DrugBank | DrugBank |
| Canada; consumer_product; Substances in Products - Canada (4/2014) | Government of Canada | CPCat |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 7 of 7 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| JAC85A2161 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| JAC85A2161 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| JAC85A2161 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| JAC85A2161 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =227 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| =227 | mg/kg bw/day | LEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =35 | mg/kg bw/day | LOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
Showing 7 of 7 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Adenine | 200-796-1 | ECHA overview → |
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Skin Conditioning
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
ADENINE
ChEMBL Phase
3
Adverse Events
0
Bioactivity
8
Frequently Asked Questions
What regulatory lists include Adenine?
Adenine appears on 2 regulatory/inventory lists including Canada; pharmaceutical, Canada; consumer_product; Substances in Products - Canada (4/2014). Source: EPA CPDat.
Is Adenine used in cosmetics?
Yes, Adenine is also indexed as a cosmetic ingredient under the name ADENINE. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Adenine come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Does Adenine have different safety status in cosmetics vs industrial chemicals?
Adenine is classified GHS Danger (H301) in the chemicals database but is allowed in EU cosmetics.
Is Adenine used outside industrial chemicals?
Adenine also appears in cosmetics, pharmaceutical databases.