Is ADENINE safe in cosmetics?
ADENINE has a safety rating of "GOOD" in our database. EU status: permitted.
GOOD
Cosmetic Ingredient
ADENINE
Also known as: Vitamin B4 (adenine), EINECS 200-796-1, 1H-Purine, 6-amino, Purine, 6-amino-, 9H-Purine, 1,6-dihydro-6-imino- (+10 more)
ADENINE (CAS 73-24-5) is a cosmetic cosmetic ingredient functioning as Skin Conditioning. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
Cross-Vertical Regulatory Divergence
ADENINE is classified GHS Danger (H301) in the chemicals database but is allowed in EU cosmetics.
Source: Cosmetics: ingredients.eu status; Chemicals: ghs classifications.signal word/hazard statement code
Function
Skin Conditioning
Editorial assessment
GOOD
Preliminary editorial note — not a computed safety verdict.
Chemistry & Identifiers
IUPAC Name
7H-purin-6-amine
InChIKey
GFFGJBXGBJISGV-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
Not specifically regulated
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
10 - 100 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Safety (1)
Carcinogen Classification
No indication of carcinogenicity to humans (not listed by IARC).
Source: Toxin and Toxin Target Database (T3DB)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Softener and conditioner
Editorial summary
Preliminary editorial summary for ADENINE — not a computed safety verdict. See the sourced toxicological data above.
Regulatory Flags
cosing-sourced
eu-permitted
skin-conditioning
needs-enrichment
Known Synonyms
Vitamin B4 (adenine)
EINECS 200-796-1
1H-Purine, 6-amino
Purine, 6-amino-
9H-Purine, 1,6-dihydro-6-imino-
UNII-JAC85A2161
1H-Purine-6-amine
6-Amino-7H-purine
6-Amino-Purine
9H-Purin-6-yl-amin
9H-Purin-6-ylamine
9H-Purine-6-amine
Ade
Adenin
Vitamin B4
Chemical Function
Softener and conditioner
Regulatory Lists
Canada; pharmaceutical
Canada; pharmaceutical
Canada; consumer_product; Substances in Products - Canada (4/2014)
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
ADENINE
ChEMBL ID
CHEMBL226345
Max Phase
3
Frequently Asked Questions
Is ADENINE allowed in the EU?
ADENINE EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does ADENINE do in cosmetics?
ADENINE functions as: Skin Conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 73-24-5.
Is ADENINE used outside cosmetics?
ADENINE also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does ADENINE have different safety status in cosmetics vs industrial chemicals?
ADENINE is classified GHS Danger (H301) in the chemicals database but is allowed in EU cosmetics.
Compliance Tools
Check ADENINE compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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