What is the NOAEL for Diallyldimethylammonium chloride?
Diallyldimethylammonium chloride has 14 NOAEL studies in the database. The lowest reported value is 8MC08B895B UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Diallyldimethylammonium chloride
Also known as: 2-Propen-1-aminium, N,N-dimethyl-N-2-propenyl-, chloride, 2-Propen-1-aminium, N,N-dimethyl-N-2-propen-1-yl-, chloride (1:1), Ammonium, diallyldimethyl-, chloride, N,N-Dimethyl-N-2-propenyl-2-propen-1-aminium chloride, EINECS 230-993-8 (+3 more)
CAS 7398-69-8
Diallyldimethylammonium chloride (CAS 7398-69-8) is a chemical substance. Key regulatory status: REACH registered, 4 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
View cosmetic safety profile for Diallyldimethyl Ammonium Chloride (DADMAC) →
SOURCE
noael studies public
NOAEL studies
14
SOURCE
chemical inventory jurisdictions
Regulatory lists
4
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
14 fields
Name
Diallyldimethylammonium chloride
CAS Number
7398-69-8
DTXSID
DTXSID4027650
Molecular Formula
C8H16N.ClH
InChI Key
GQOKIYDTHHZSCJ-UHFFFAOYSA-M
Monoisotopic Mass
162.104952
Synonyms
2-Propen-1-aminium, N,N-dimethyl-N-2-propenyl-, chloride2-Propen-1-aminium, N,N-dimethyl-N-2-propen-1-yl-, chloride (1:1)Ammonium, diallyldimethyl-, chlorideN,N-Dimethyl-N-2-propenyl-2-propen-1-aminium chlorideEINECS 230-993-8NSC 59284UNII-8MC08B895BDimethyldiallylammonium chloride
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
4 records
Surfactant (surface active agent)BiocideNo specific technical function
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
4 records
| List | Keyword | Source |
|---|---|---|
| CEDI | FDA | United States Food and Drug Administration (FDA) |
| Indirect additives food contact (10/2018) | FDA | United States Food and Drug Administration (FDA) |
| Cleaning products and household care - dishwasher and dishes - automatic dishwashing detergent; Europe | Danish EPA | Danish EPA |
| fracking; water | NY Department of Conservation | CPCat |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 14 of 14 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 8MC08B895B | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 8MC08B895B | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 8MC08B895B | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 8MC08B895B | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =2520 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| =3930 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| >10000 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| =500 | mg/kg bw/day | LOAEL | oral | Rat | ToxValDB_HPVIS |
| =800 | mg/kg bw/day | LOAEL | oral | Dog | ToxValDB_ECHA_IUCLID |
| - | unitless | Model Score | - | - | NTP_ICE_endocrine |
| =1.25 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_HPVIS |
| =6 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_HPVIS |
| =50 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_HPVIS |
| =200 | mg/kg bw/day | NOAEL | oral | Dog | ToxValDB_ECHA_IUCLID |
Showing 14 of 14 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Diallyldimethylammonium chloride | 230-993-8 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
restricted
Max
-
Category
Hair Conditioning
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL3185104
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Frequently Asked Questions
What regulatory lists include Diallyldimethylammonium chloride?
Diallyldimethylammonium chloride appears on 4 regulatory/inventory lists including CEDI, Indirect additives food contact (10/2018), Cleaning products and household care - dishwasher and dishes - automatic dishwashing detergent; Europe, and 1 more. Source: EPA CPDat.
Is Diallyldimethylammonium chloride used in cosmetics?
Yes, Diallyldimethylammonium chloride is also indexed as a cosmetic ingredient under the name Diallyldimethyl Ammonium Chloride (DADMAC). View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Diallyldimethylammonium chloride come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Is Diallyldimethylammonium chloride used outside industrial chemicals?
Diallyldimethylammonium chloride also appears in cosmetics, pharmaceutical databases.