Is Diallyldimethyl Ammonium Chloride (DADMAC) safe in cosmetics?
Diallyldimethyl Ammonium Chloride (DADMAC) has a safety rating of "MODERATE" in our database. EU status: restricted. US status: restricted.
Moderate
Cosmetic Ingredient
Diallyldimethyl Ammonium Chloride (DADMAC)
Also known as: 2-Propen-1-aminium, N,N-dimethyl-N-2-propenyl-, chloride, 2-Propen-1-aminium, N,N-dimethyl-N-2-propen-1-yl-, chloride (1:1), Ammonium, diallyldimethyl-, chloride, N,N-Dimethyl-N-2-propenyl-2-propen-1-aminium chloride, EINECS 230-993-8 (+3 more)
INCI: DIALLYLDIMETHYLAMMONIUM CHLORIDE
Diallyldimethyl Ammonium Chloride (DADMAC) (CAS 7398-69-8) is a cosmetic cosmetic ingredient functioning as Antistatic agent, hair conditioning (monomer for Polyquaternium-6). NOAEL 200 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: restricted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 7398-69-8 →
Auto-generated CPSR Part A draft with source citations
Function
Antistatic agent, hair conditioning (monomer for Polyquaternium-6)
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
dimethyl-bis(prop-2-enyl)azanium chloride
InChIKey
GQOKIYDTHHZSCJ-UHFFFAOYSA-M
Regulatory Status
EU EU Status
restricted
US US Status
restricted
US Notes
Permitted as a monomer precursor in polymerized forms; not specifically restricted; EPA-registered for water treatment applications
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Diallyldimethyl Ammonium Chloride (DADMAC).
Calculate MoS for your specific formulation with the MoS Calculator.
Pre-Calculated Safety Assessment
Pre-calculated NOAEL → SED → MoS audit trail for Diallyldimethyl Ammonium Chloride (DADMAC) across SCCS product categories, with measured dermal absorption where available.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
1,000 - 10,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Biocide
No specific technical function
Surfactant (surface active agent)
Regulatory List Membership (1)
FDA Indirect Food Contact Additives
Expert Verdict
Expert safety assessment and concern-level summary for Diallyldimethyl Ammonium Chloride (DADMAC).
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to Diallyldimethyl Ammonium Chloride (DADMAC) by CAS number or substance name.
Studies
6
Lowest NOAEL
200 mg/kg bw/day
Highest NOAEL
1000 mg/kg bw/day
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip
Known Synonyms
2-Propen-1-aminium, N,N-dimethyl-N-2-propenyl-, chloride
2-Propen-1-aminium, N,N-dimethyl-N-2-propen-1-yl-, chloride (1:1)
Ammonium, diallyldimethyl-, chloride
N,N-Dimethyl-N-2-propenyl-2-propen-1-aminium chloride
EINECS 230-993-8
NSC 59284
UNII-8MC08B895B
Dimethyldiallylammonium chloride
Chemical Function
Surfactant (surface active agent)
Biocide
No specific technical function
Regulatory Lists
CEDI
Indirect additives food contact (10/2018)
Cleaning products and household care - dishwasher and dishes - automatic dishwashing detergent; Europe
fracking; water
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL3185104
Frequently Asked Questions
Is Diallyldimethyl Ammonium Chloride (DADMAC) allowed in the EU?
Diallyldimethyl Ammonium Chloride (DADMAC) EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.
What does Diallyldimethyl Ammonium Chloride (DADMAC) do in cosmetics?
Diallyldimethyl Ammonium Chloride (DADMAC) functions as: Antistatic agent, hair conditioning (monomer for Polyquaternium-6). It is classified as a cosmetic ingredient in our database. CAS number: 7398-69-8.
Is Diallyldimethyl Ammonium Chloride (DADMAC) used outside cosmetics?
Diallyldimethyl Ammonium Chloride (DADMAC) also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Diallyldimethyl Ammonium Chloride (DADMAC) compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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DIALLYLDIMETHYL AMMONIUM CHLORIDE
Good
Chemical family
Not Reported
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