What is the GHS hazard classification for Ethane?
Ethane (CAS 74-84-0) is classified under EU CLP Annex VI as Flam. Gas 1; Press. Gas with signal word Danger. Hazard statements: H220. Source: EU CLP Annex VI (ECHA).
Danger
GHS02GHS04
NOAEL Data
REACH Registered
Cosmetic Ingredient
Ethane
Also known as: EINECS 200-814-8, UNII-L99N5N533T, R-170
CAS 74-84-0
Ethane (CAS 74-84-0) is a chemical substance with GHS signal word Danger; key hazard signal: H220. Key regulatory status: REACH registered, 1 regulatory/inventory list, cosmetic ingredient cross-reference; source data from ECHA CLP, EPA ToxValDB, EPA CPDat, ECHA REACH, ILO ICSC.
Cross-Vertical Regulatory Divergence
Ethane is classified GHS Danger (H220) in the chemicals database but is restricted in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: eu_clp_annex_vi.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
23
SOURCE
chemical inventory jurisdictions
Regulatory lists
1
SOURCE
eu clp annex vi
GHS signal
Danger
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
9 fields
Name
Ethane
CAS Number
74-84-0
DTXSID
DTXSID6026377
Molecular Formula
C2H6
InChI Key
OTMSDBZUPAUEDD-UHFFFAOYSA-N
Monoisotopic Mass
30.04695
Synonyms
EINECS 200-814-8UNII-L99N5N533TR-170
GHS / CLP Classification
EU harmonized hazard classification, hazard statements, pictograms, and signal word.
SOURCE
EU CLP Annex VI (ECHA)
1 classifications
| Hazard Class | H-Statements | Pictograms | Signal |
|---|---|---|---|
| Flam. Gas 1; Press. Gas | H220 | GHS02; GHS04 | Danger |
ICSC Chemical Safety
International Chemical Safety Card hazard and exposure summary.
SOURCE
ILO/WHO International Chemical Safety Cards
1 records
| Field | Value |
|---|---|
| GHS Signal Word | DANGER |
| GHS Hazard Statements | Extremely flammable gas Contains gas under pressure; may explode if heated |
| Short-term Effects | Rapid evaporation of the liquid may cause frostbite. |
| Routes of Exposure | The substance can be absorbed into the body by inhalation. |
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
3 records
Propellants, non-motive (blowing agents)
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
1 records
| List | Keyword | Source |
|---|---|---|
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 23 of 23 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 150 | uL/min/10^6 cells | Clint | - | Human | NTP_ICE_adme_parameters |
| L99N5N533T | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| L99N5N533T | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| L99N5N533T | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| L99N5N533T | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =36895.9 | mg/m3 | LEL | inhalation | Human | ToxValDB_DOE_Protective_Action_Criteria |
| =245973 | mg/m3 | LEL | inhalation | Rat | ToxValDB_ECHA_IUCLID |
| =344362 | mg/m3 | LEL | inhalation | Rat | ToxValDB_ECHA_IUCLID |
| =606687 | mg/m3 | LEL | inhalation | Cat | ToxValDB_ECHA_IUCLID |
| =642000 | mg/m3 | LEL | inhalation | Rat | ToxValDB_ECHA_IUCLID |
| =14758.4 | mg/m3 | LOAEC | inhalation | Rat | ToxValDB_ECHA_IUCLID |
| =21641 | mg/m3 | LOAEC | inhalation | Rat | ToxValDB_ECHA_IUCLID |
| =4919.45 | mg/m3 | NOAEC | inhalation | Rat | ToxValDB_ECHA_IUCLID |
| =5456.9 | mg/m3 | NOAEC | inhalation | Rat | ToxValDB_ECHA_IUCLID |
| =7214 | mg/m3 | NOAEC | inhalation | Rat | ToxValDB_ECHA_IUCLID |
| =11068.8 | mg/m3 | NOAEC | inhalation | Rat | ToxValDB_ECHA_IUCLID |
| =11800 | mg/m3 | NOAEC | inhalation | Rat | ToxValDB_ECHA_IUCLID |
| =12298.6 | mg/m3 | NOAEC | inhalation | Rat | ToxValDB_ECHA_IUCLID |
| =14758.4 | mg/m3 | NOAEC | inhalation | Rat | ToxValDB_ECHA_IUCLID |
| =19677.8 | mg/m3 | NOAEC | inhalation | Rat | ToxValDB_ECHA_IUCLID |
| =19678 | mg/m3 | NOAEC | inhalation | Rat | ToxValDB_ECHA_IUCLID |
| =21394 | mg/m3 | NOAEC | inhalation | Rat | ToxValDB_ECHA_IUCLID |
| =21641 | mg/m3 | NOAEC | inhalation | Rat | ToxValDB_ECHA_IUCLID |
Showing 23 of 23 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Ethane | 200-814-8 | ECHA overview → |
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
restricted
Max
-
Category
Cosmetic Ingredient
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
ETHANE
ChEMBL Phase
2
Adverse Events
0
Bioactivity
0
Frequently Asked Questions
What is the NOAEL for Ethane?
Ethane has 23 NOAEL studies in the database. The lowest reported value is 150 uL/min/10^6 cells in Human. Source: NTP_ICE_adme_parameters.
What regulatory lists include Ethane?
Ethane appears on 1 regulatory/inventory list including inert_ingredient; non_food_use; Pesticides. Source: EPA CPDat.
Is Ethane used in cosmetics?
Yes, Ethane is also indexed as a cosmetic ingredient under the name Ethane. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Ethane come from?
Safety data is sourced from ECHA CLP Annex VI, EPA ToxValDB, EPA CPDat, EPA DSSTox, ECHA REACH, ILO/WHO ICSC, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Does Ethane have different safety status in cosmetics vs industrial chemicals?
Ethane is classified GHS Danger (H220) in the chemicals database but is restricted in EU cosmetics.
Is Ethane used outside industrial chemicals?
Ethane also appears in cosmetics, pharmaceutical databases.