What is the NOAEL for 1,1-Dimethoxy-3,7-dimethylocta-2,6-diene?
1,1-Dimethoxy-3,7-dimethylocta-2,6-diene has 8 NOAEL studies in the database. The lowest reported value is 6ZOD5NW633 UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
1,1-Dimethoxy-3,7-dimethylocta-2,6-diene
Also known as: 2,6-Octadiene, 1,1-dimethoxy-3,7-dimethyl-, Citral dimethyl acetal, 4-01-00-03570, BRN 1706336, 1,1-Dimethoxy-3,7-dimethyl-2,6-octadiene (+5 more)
CAS 7549-37-3
1,1-Dimethoxy-3,7-dimethylocta-2,6-diene (CAS 7549-37-3) is a chemical substance. Key regulatory status: 4 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
SOURCE
noael studies public
NOAEL studies
8
SOURCE
chemical inventory jurisdictions
Regulatory lists
4
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
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DSSTox identifiers
16 fields
Name
1,1-Dimethoxy-3,7-dimethylocta-2,6-diene
CAS Number
7549-37-3
DTXSID
DTXSID8044832
Molecular Formula
C12H22O2
InChI Key
ZSKAJFSSXURRGL-UHFFFAOYSA-N
Monoisotopic Mass
198.16198
Synonyms
2,6-Octadiene, 1,1-dimethoxy-3,7-dimethyl-Citral dimethyl acetal4-01-00-03570BRN 17063361,1-Dimethoxy-3,7-dimethyl-2,6-octadiene3,7-Dimethyl-2,6-octadienal dimethyl acetalEINECS 231-434-0FEMA No. 23052,6-Octadienal, 3,7-dimethyl-, dimethyl acetalUNII-6ZOD5NW633
Functional Uses
Industrial and product-use categories associated with this substance.
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EPA CPDat
5 records
FragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
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EPA CPDat
4 records
| List | Keyword | Source |
|---|---|---|
| IFRA Transparency | IFRA | IFRA |
| Europe | European Commission | Fl@vis |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| consumer_product | P&G | Proctor & Gamble |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
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NOAEL studies
Showing 8 of 8 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 6ZOD5NW633 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 6ZOD5NW633 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 6ZOD5NW633 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 6ZOD5NW633 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 2592 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| 1500 | mg/kg bw/day | NOAEL | oral | mouse | COSMOS_DB |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
Showing 8 of 8 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
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AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
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CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
ADI: No safety concern at current levels of intake when used as a flavouring agent mg/kg bw
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
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Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include 1,1-Dimethoxy-3,7-dimethylocta-2,6-diene?
1,1-Dimethoxy-3,7-dimethylocta-2,6-diene appears on 4 regulatory/inventory lists including IFRA Transparency, Europe, food_additive; Substances Added to Food (formerly EAFUS) (2/2019), and 1 more. Source: EPA CPDat.
Is 1,1-Dimethoxy-3,7-dimethylocta-2,6-diene used in cosmetics?
Yes, 1,1-Dimethoxy-3,7-dimethylocta-2,6-diene is also indexed as a cosmetic ingredient under the name Citral Dimethyl Acetal. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 1,1-Dimethoxy-3,7-dimethylocta-2,6-diene come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is 1,1-Dimethoxy-3,7-dimethylocta-2,6-diene used outside industrial chemicals?
1,1-Dimethoxy-3,7-dimethylocta-2,6-diene also appears in cosmetics, food safety, cannabis databases.