What is the NOAEL for Potassium iodide?
Potassium iodide has 25 NOAEL studies in the database. The lowest reported value is 0.07 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Potassium iodide
Also known as: Caswell No. 694, Dipotassium diiodide, EINECS 231-659-4, EPA Pesticide Chemical Code 075701, Joptone (+9 more)
CAS 7681-11-0
Potassium iodide (CAS 7681-11-0) is a chemical substance. Key regulatory status: REACH registered, 9 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
Cross-Vertical Regulatory Divergence
Potassium iodide is classified GHS Danger (H302, H315, H317, H319, H334, H372, H373, H411) in the chemicals database but is allowed in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
25
SOURCE
chemical inventory jurisdictions
Regulatory lists
9
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
20 fields
Name
Potassium iodide
CAS Number
7681-11-0
DTXSID
DTXSID7034836
Molecular Formula
HI.K
InChI Key
NLKNQRATVPKPDG-UHFFFAOYSA-M
Monoisotopic Mass
166.876003
Synonyms
Caswell No. 694Dipotassium diiodideEINECS 231-659-4EPA Pesticide Chemical Code 075701JoptoneKali iodideKalii iodidumPotassium diiodideTripotassium triiodideThyrosafeThyroshieldUNII-1C4QK22F9J
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
36 records
Stabilizing agentBiocideNo specific technical functionFlavouring and nutrientProcessing aids not otherwise specifiedTracer
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
9 records
| List | Keyword | Source |
|---|---|---|
| drinking_water; Europe; manufacturing; plastic_additive | Belgaqua | CPCat |
| active_ingredient; Europe; Pesticides | European Commission | CPCat |
| active_ingredient; Europe; Pesticides | Commission of the European Communities | CPCat |
| Europe; supplements | EU | CPCat |
| Europe; food_additive; supplements | EU | CPCat |
| Europe; plastic_additive | European Chemicals Agency | European Chemicals Agency (ECHA) |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| Canada; pharmaceutical | DrugBank | DrugBank |
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 25 of 25 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =0.07 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| =0.493 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| 1C4QK22F9J | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 1C4QK22F9J | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 1C4QK22F9J | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 1C4QK22F9J | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =5 | mg/kg bw/day | LEL | oral | Chicken | ToxValDB_EFSA |
| =8 | mg/kg bw/day | LEL | oral | Pig | ToxValDB_EFSA |
| =0.3 | mg | LOEL | injection | Dog | ToxValDB_ECOTOX |
| =5.6 | mg/kg dry food | LOEL | oral | Dog | ToxValDB_ECOTOX |
| =1000 | ppm | LOEL | oral | Rat | ToxValDB_ECOTOX |
| =0.5 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_EFSA |
| =0.5 | mg/kg bw/day | NOAEL | - | American mink | EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx |
| =0.5 | mg/kg bw/day | NOAEL | - | American mink | EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx |
| 3 | mg/kg bw/day | NOAEL | oral | mink | COSMOS_DB |
| 6 | mg/kg bw/day | NOAEL | oral | syrian hamster | COSMOS_DB |
| 7.5 | mg/kg bw/day | NOAEL | oral | rabbit | COSMOS_DB |
| 25 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
| 26 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
| 41 | mg/kg bw/day | NOAEL | oral | swine | COSMOS_DB |
| 42 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
| <2.23 | mg/kg bw/day | NOEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =20 | mg/kg bw/day | NOEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =250 | ppm | NOEL | oral | Rat | ToxValDB_ECOTOX |
| =500 | ppm | NOEL | oral | Rat | ToxValDB_ECOTOX |
Showing 25 of 25 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Potassium iodide | 231-659-4 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Skin Conditioning
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
POTASSIUM IODIDE
ChEMBL Phase
4
Adverse Events
349
Bioactivity
2
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
1 food-safety record found.
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Potassium iodide?
Potassium iodide appears on 8 regulatory/inventory lists including drinking_water; Europe; manufacturing; plastic_additive, active_ingredient; Europe; Pesticides, Europe; supplements, and 5 more. Source: EPA CPDat.
Is Potassium iodide used in cosmetics?
Yes, Potassium iodide is also indexed as a cosmetic ingredient under the name Potassium Iodide. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Potassium iodide come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Does Potassium iodide have different safety status in cosmetics vs industrial chemicals?
Potassium iodide is classified GHS Danger (H302, H315, H317, H319, H334, H372, H373, H411) in the chemicals database but is allowed in EU cosmetics.
Is Potassium iodide used outside industrial chemicals?
Potassium iodide also appears in cosmetics, pharmaceutical, food safety, cannabis databases.