Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
10 study endpoints found for Potassium Iodide. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 75 mg/kg bw/day | oral | rat | Reproductive | COSMOS_DB |
| NOAEL | 25 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
| NOAEL | 6 mg/kg bw/day | oral | syrian hamster | Carcinogenicity | COSMOS_DB |
| NOAEL | 125 mg/kg bw/day | oral | rat | Reproductive | COSMOS_DB |
| NOAEL | 125 mg/kg bw/day | oral | rat | Reproductive | COSMOS_DB |
| NOAEL | 125 mg/kg bw/day | oral | rat | Reproductive | COSMOS_DB |
| NOAEL | 7.5 mg/kg bw/day | oral | rabbit | Reproductive | COSMOS_DB |
| NOAEL | 160 mg/kg bw/day | oral | syrian hamster | Reproductive | COSMOS_DB |
| NOAEL | 150 mg/kg bw/day | oral | rat | Reproductive | COSMOS_DB |
| NOAEL | 41 mg/kg bw/day | oral | swine | Reproductive | COSMOS_DB |
Expert Verdict
Thyroid disruption risk with excessive or prolonged dermal exposure; contraindicated for individuals with thyroid disorders; iododerma risk; systemic absorption is a significant concern
Regulatory Flags
Frequently Asked Questions
Is Potassium Iodide safe in cosmetics?
Thyroid disruption risk with excessive or prolonged dermal exposure; contraindicated for individuals with thyroid disorders; iododerma risk; systemic absorption is a significant concern The EU classifies Potassium Iodide as "permitted". Safety rating: MODERATE. 10 toxicological study endpoint(s) are available in our database.
Is Potassium Iodide allowed in the EU?
Potassium Iodide EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Potassium Iodide do in cosmetics?
Potassium Iodide functions as: Skin conditioning; also used as an oxidizing agent in cosmetics. It is classified as a cosmetic ingredient in our database. CAS number: 7681-11-0.
What is the Margin of Safety for Potassium Iodide?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Potassium Iodide?
The NOAEL (No Observed Adverse Effect Level) for Potassium Iodide is 75 mg/kg bw/day based on a Reproductive study via oral route in rat. A total of 10 study endpoints are available. Source: COSMOS_DB.
Compliance Tools
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Related Ingredients
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