What is the NOAEL for Stannous chloride?
Stannous chloride has 39 NOAEL studies in the database. The lowest reported value is 1 mg/m3 via inhalation in Human. Source: ToxValDB GESTIS DNEL.
Also known as: Tin(II) chloride, Tin chloride (SnCl2), EINECS 231-868-0, NCI-C02722, Stannous chloride, anhydrous (+8 more)
CAS 7772-99-8
Stannous chloride (CAS 7772-99-8) is a chemical substance. Key regulatory status: REACH registered, 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH, ILO ICSC.
Stannous chloride is classified GHS Danger (H290, H302, H332, H312, H314, H317, H318, H319) in the chemicals database but is allowed in EU cosmetics.
CAS, identifiers, formula, and alternate names for the matched substance record.
International Chemical Safety Card hazard and exposure summary.
| Field | Value |
|---|---|
| Short-term Effects | The substance is irritating to the eyes and respiratory tract. |
| Routes of Exposure | The substance can be absorbed into the body by inhalation of its aerosol and by ingestion. |
Industrial and product-use categories associated with this substance.
Inventory, screening, and regulatory list matches from public chemical databases.
| List | Keyword | Source |
|---|---|---|
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| Canada; pharmaceutical | DrugBank | DrugBank |
Toxicology endpoints rendered from public NOAEL study rows.
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =1 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB GESTIS DNEL |
| R30H55TN67 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =0.13 | mg/m3 | LOAEL | inhalation | Human; Mouse | WHO/JECFA |
| =0.2 | mg/kg bw | LOAEL | subcutaneous | Rat | WHO/JECFA |
| =250 | umol/kg bw | LOEL | injection | Rat | ToxValDB ECOTOX |
| =0.014 | mg/m3 | NOAEL | inhalation | - | WHO/JECFA |
| 1.25 | mg/kg bw/day | NOAEL | oral | mouse | COSMOS DB |
| 2 | mg/kg bw/day | NOAEL | oral | rat | COSMOS DB |
| 6 | mg/kg bw/day | NOAEL | oral | rat | COSMOS DB |
| 16 | mg/kg bw/day | NOAEL | oral | rat | COSMOS DB |
| 20 | mg/kg bw/day | NOAEL | oral | rabbit | COSMOS DB |
| 25 | mg/kg bw/day | NOAEL | oral | rat | COSMOS DB |
| 32 | mg/kg bw/day | NOAEL | oral | rat | COSMOS DB |
| =32.14 | mg/kg bw/day | NOAEL | - | Mouse | WHO/JECFA |
| 41.5 | mg/kg bw/day | NOAEL | oral | rabbit | COSMOS DB |
| 50 | mg/kg bw/day | NOAEL | oral | mouse | COSMOS DB |
| >50 | mg/kg bw/day | NOAEL | oral | Rat | ECHA |
| 60 | mg/kg bw/day | NOAEL | oral | rat | COSMOS DB |
| =63 | mg/kg bw/day | NOAEL | oral | Rat | EFSA |
| =63 | mg/kg bw/day | NOAEL | oral: feed | Rat | EFSA |
| 64 | mg/kg bw/day | NOAEL | oral | rat | COSMOS DB |
| 94 | mg/kg bw/day | NOAEL | oral | rat | COSMOS DB |
| 100 | mg/kg bw/day | NOAEL | oral | rat | COSMOS DB |
| 125 | mg/kg bw/day | NOAEL | oral | rat | COSMOS DB |
| 150 | mg/kg bw/day | NOAEL | oral | rat | COSMOS DB |
| =240 | mg/kg bw/day | NOAEL | oral | Rat | ECHA |
| 246 | mg/kg bw/day | NOAEL | oral | rat | COSMOS DB |
| 300 | mg/kg bw/day | NOAEL | oral | rat | COSMOS DB |
| 320 | mg/kg bw/day | NOAEL | oral | rat | COSMOS DB |
| =350 | mg/kg bw/day | NOAEL | - | Rat | WHO/JECFA |
| 380 | mg/kg bw/day | NOAEL | oral | rat | COSMOS DB |
| =576 | mg/kg bw/day | NOAEL | oral | Rat | ECHA |
| 2250 | mg/kg bw/day | NOAEL | oral | mouse | COSMOS DB |
| 3000 | mg/kg bw/day | NOAEL | oral | rat | COSMOS DB |
| 4500 | mg/kg bw/day | NOAEL | oral | mouse | COSMOS DB |
| =0.28 | ug/g wet wt diet | NOEL | oral | Mouse | ToxValDB ECOTOX |
| =200 | mg/kg bw/day | NOEL | oral | European Rabbit | ToxValDB ECOTOX |
| =364.8 | mg/kg bw/day | NOEL | oral | Rat | ToxValDB HESS |
| 2000 | ppm | Top dose | Dosed feed | Rat | NTP ICE cancer |
Showing 39 of 39 studies
Registration status from the ECHA REACH registered substances database.
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Tin dichloride | 231-868-0 | ECHA overview → |
Australian industrial chemicals inventory status and applicable conditions.
Same-CAS cosmetic ingredient record for cross-vertical context.
Same-CAS food additive, ADI, and GRAS records where available.
E512 — ADI: 14 mg/kg bw
View full food safety profile →Same-CAS cannabis compliance and lab records where available.
1 cannabis record found in efsa substances.
View full cannabis profile →Stannous chloride has 39 NOAEL studies in the database. The lowest reported value is 1 mg/m3 via inhalation in Human. Source: ToxValDB GESTIS DNEL.
Stannous chloride appears on 2 regulatory/inventory lists including food_additive; Substances Added to Food (formerly EAFUS) (2/2019), Canada; pharmaceutical. Source: EPA CPDat.
Yes, Stannous chloride is also indexed as a cosmetic ingredient under the name Stannous Chloride. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, ILO/WHO ICSC, CosIng / Ingredients DB, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Stannous chloride is classified GHS Danger (H290, H302, H332, H312, H314, H317, H318, H319) in the chemicals database but is allowed in EU cosmetics.
Stannous chloride also appears in cosmetics, food safety, cannabis databases.