What is the NOAEL for Stannous chloride?
Stannous chloride has 57 NOAEL studies in the database. The lowest reported value is 1 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Stannous chloride
Also known as: Tin(II) chloride, Tin chloride (SnCl2), EINECS 231-868-0, NCI-C02722, Stannous chloride, anhydrous (+8 more)
CAS 7772-99-8
Stannous chloride (CAS 7772-99-8) is a chemical substance. Key regulatory status: REACH registered, 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH, ILO ICSC.
Cross-Vertical Regulatory Divergence
Stannous chloride is classified GHS Danger (H290, H302, H332, H312, H314, H317, H318, H319) in the chemicals database but is allowed in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
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noael studies public
NOAEL studies
57
SOURCE
chemical inventory jurisdictions
Regulatory lists
2
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
19 fields
Name
Stannous chloride
CAS Number
7772-99-8
DTXSID
DTXSID8021351
Molecular Formula
2ClH.Sn
InChI Key
AXZWODMDQAVCJE-UHFFFAOYSA-L
Monoisotopic Mass
191.855557
Synonyms
Tin(II) chlorideTin chloride (SnCl2)EINECS 231-868-0NCI-C02722Stannous chloride, anhydrousUNII-R30H55TN67SnCl2stannous chloride (anh.)stannous chloride (anhydrous)tin dichloride (anhydrous)tin(II) chloride (anh.)tin(II) chloride (anhydrous)
ICSC Chemical Safety
International Chemical Safety Card hazard and exposure summary.
SOURCE
ILO/WHO International Chemical Safety Cards
1 records
| Field | Value |
|---|---|
| Short-term Effects | The substance is irritating to the eyes and respiratory tract. |
| Routes of Exposure | The substance can be absorbed into the body by inhalation of its aerosol and by ingestion. |
Functional Uses
Industrial and product-use categories associated with this substance.
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EPA CPDat
9 records
Reducing agentNo specific technical functionCatalystAntioxidant
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
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EPA CPDat
2 records
| List | Keyword | Source |
|---|---|---|
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| Canada; pharmaceutical | DrugBank | DrugBank |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 50 of 57 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =1 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| R30H55TN67 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| R30H55TN67 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| R30H55TN67 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| R30H55TN67 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =0.13 | mg/m3 | LOAEL | inhalation | Human; Mouse | INCHEM_WHO_kemi_kemi_ah2005_07 |
| =0.13 | mg/m3 | LOAEL | inhalation | Human; Mouse | INCHEM_WHO_kemi_kemi_ah2005_07 |
| =0.13 | mg/m3 | LOAEL | inhalation | Human; Mouse | INCHEM_WHO_kemi_kemi_ah2005_07 |
| =0.13 | mg/m3 | LOAEL | inhalation | Human; Mouse | INCHEM_WHO_kemi_kemi_ah2005_07 |
| =0.2 | mg/kg bw | LOAEL | subcutaneous | Rat | INCHEM_WHO_kemi_kemi_ah2005_07 |
| =0.2 | mg/kg bw | LOAEL | subcutaneous | Rat | INCHEM_WHO_kemi_kemi_ah2005_07 |
| =0.2 | mg/kg bw | LOAEL | subcutaneous | Rat | INCHEM_WHO_kemi_kemi_ah2005_07 |
| =0.2 | mg/kg bw | LOAEL | subcutaneous | Rat | INCHEM_WHO_kemi_kemi_ah2005_07 |
| =250 | umol/kg bw | LOEL | injection | Rat | ToxValDB_ECOTOX |
| =0.014 | mg/m3 | NOAEL | inhalation | - | INCHEM_WHO_kemi_kemi_ah2005_07 |
| =0.014 | mg/m3 | NOAEL | inhalation | - | INCHEM_WHO_kemi_kemi_ah2005_07 |
| =0.014 | mg/m3 | NOAEL | inhalation | - | INCHEM_WHO_kemi_kemi_ah2005_07 |
| =0.014 | mg/m3 | NOAEL | inhalation | - | INCHEM_WHO_kemi_kemi_ah2005_07 |
| 1.25 | mg/kg bw/day | NOAEL | oral | mouse | COSMOS_DB |
| 2 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
| 6 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
| 16 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
| 20 | mg/kg bw/day | NOAEL | oral | rabbit | COSMOS_DB |
| 25 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
| 32 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
| =32.1428571428571 | mg/kg bw/day | NOAEL | - | Mouse | INCHEM_WHO_kemi_kemi_ah2005_07 |
| =32.1428571428571 | mg/kg bw/day | NOAEL | - | Mouse | INCHEM_WHO_kemi_kemi_ah2005_07 |
| =32.1428571428571 | mg/kg bw/day | NOAEL | - | Mouse | INCHEM_WHO_kemi_kemi_ah2005_07 |
| =32.1428571428571 | mg/kg bw/day | NOAEL | - | Mouse | INCHEM_WHO_kemi_kemi_ah2005_07 |
| 41.5 | mg/kg bw/day | NOAEL | oral | rabbit | COSMOS_DB |
| 50 | mg/kg bw/day | NOAEL | oral | mouse | COSMOS_DB |
| >50 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| 60 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
| =63 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_EFSA |
| =63 | mg/kg bw/day | NOAEL | oral: feed | Rat | EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx |
| 64 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
| 94 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
| 100 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
| 125 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
| 150 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
| =240 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| 246 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
| 300 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
| 320 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
| =350 | mg/kg bw/day | NOAEL | - | Rat | INCHEM_WHO_kemi_kemi_ah2005_07 |
| =350 | mg/kg bw/day | NOAEL | - | Rat | INCHEM_WHO_kemi_kemi_ah2005_07 |
| =350 | mg/kg bw/day | NOAEL | - | Rat | INCHEM_WHO_kemi_kemi_ah2005_07 |
| =350 | mg/kg bw/day | NOAEL | - | Rat | INCHEM_WHO_kemi_kemi_ah2005_07 |
| 380 | mg/kg bw/day | NOAEL | oral | rat | COSMOS_DB |
| =576 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
Showing 50 of 57 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Tin dichloride | 231-868-0 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
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AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
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CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Cosmetic Ingredient
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
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EFSA / FDA GRAS
1 records
E512 — ADI: 14 mg/kg bw
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Stannous chloride?
Stannous chloride appears on 2 regulatory/inventory lists including food_additive; Substances Added to Food (formerly EAFUS) (2/2019), Canada; pharmaceutical. Source: EPA CPDat.
Is Stannous chloride used in cosmetics?
Yes, Stannous chloride is also indexed as a cosmetic ingredient under the name Stannous Chloride. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Stannous chloride come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, ILO/WHO ICSC, CosIng / Ingredients DB, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Does Stannous chloride have different safety status in cosmetics vs industrial chemicals?
Stannous chloride is classified GHS Danger (H290, H302, H332, H312, H314, H317, H318, H319) in the chemicals database but is allowed in EU cosmetics.
Is Stannous chloride used outside industrial chemicals?
Stannous chloride also appears in cosmetics, food safety, cannabis databases.