NOAEL Data Cosmetic Ingredient

Propanoic acid, 2-methyl-, 1-methyl-1-(4-methyl-3-cyclohexen-1-yl)ethyl ester

CAS 7774-65-4

Propanoic acid, 2-methyl-, 1-methyl-1-(4-methyl-3-cyclohexen-1-yl)ethyl ester (CAS 7774-65-4) is a chemical substance. Key regulatory status: 4 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.

View cosmetic safety profile for Terpinyl Isobutyrate →

SOURCE noael studies public
NOAEL studies
7
SOURCE chemical inventory jurisdictions
Regulatory lists
4
SOURCE eu clp annex vi
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 6 fields
Name
Propanoic acid, 2-methyl-, 1-methyl-1-(4-methyl-3-cyclohexen-1-yl)ethyl ester
CAS Number
7774-65-4
DTXSID
DTXSID50864114
Molecular Formula
C14H24O2
InChI Key
SMQUXKIIXFOJKI-UHFFFAOYSA-N
Monoisotopic Mass
224.17763

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 5 records
FragranceFlavouring and nutrient

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 4 records
ListKeywordSource
EuropeEuropean CommissionFl@vis
IFRA TransparencyIFRAIFRA
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)FDAUnited States Food and Drug Administration (FDA)
consumer_productP&GProctor & Gamble

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 7 of 7 studies
ValueUnitEndpointRouteSpeciesSource
Z55SZR66DGUNIIFDA UNII substance identifier--openFDA substances
Z55SZR66DGUNIIFDA UNII substance identifier--openFDA substances
Z55SZR66DGUNIIFDA UNII substance identifier--openFDA substances
Z55SZR66DGUNIIFDA UNII substance identifier--openFDA substances
-%Incidence of positive responsesDermalHumanNTP_ICE_skin_sensitization
6750ug/cm2Induction dose per skin areaDermalHumanNTP_ICE_skin_sensitization
3unitlessRelative reliability scoreDermalHumanNTP_ICE_skin_sensitization

Showing 7 of 7 studies

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
View full cosmetic safety profile →

Pharmaceutical Data

Same-CAS pharmaceutical records from drug and bioactivity sources.

SOURCE EMBL-EBI ChEMBL CHEMBL4169675
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
View full pharmaceutical profile →

Food Safety Data

Same-CAS food additive, ADI, and GRAS records where available.

SOURCE EFSA / FDA GRAS 1 records

ADI: No safety concern at current levels of intake when used as a flavouring agent mg/kg bw

View full food safety profile →

Frequently Asked Questions

What is the NOAEL for Propanoic acid, 2-methyl-, 1-methyl-1-(4-methyl-3-cyclohexen-1-yl)ethyl ester?

Propanoic acid, 2-methyl-, 1-methyl-1-(4-methyl-3-cyclohexen-1-yl)ethyl ester has 7 NOAEL studies in the database. The lowest reported value is Z55SZR66DG UNII. Source: openFDA substances.

What regulatory lists include Propanoic acid, 2-methyl-, 1-methyl-1-(4-methyl-3-cyclohexen-1-yl)ethyl ester?

Propanoic acid, 2-methyl-, 1-methyl-1-(4-methyl-3-cyclohexen-1-yl)ethyl ester appears on 4 regulatory/inventory lists including Europe, IFRA Transparency, food_additive; Substances Added to Food (formerly EAFUS) (2/2019), and 1 more. Source: EPA CPDat.

Is Propanoic acid, 2-methyl-, 1-methyl-1-(4-methyl-3-cyclohexen-1-yl)ethyl ester used in cosmetics?

Yes, Propanoic acid, 2-methyl-, 1-methyl-1-(4-methyl-3-cyclohexen-1-yl)ethyl ester is also indexed as a cosmetic ingredient under the name Terpinyl Isobutyrate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Propanoic acid, 2-methyl-, 1-methyl-1-(4-methyl-3-cyclohexen-1-yl)ethyl ester come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS. All data traces to primary regulatory sources and is updated from official government databases.

Is Propanoic acid, 2-methyl-, 1-methyl-1-(4-methyl-3-cyclohexen-1-yl)ethyl ester used outside industrial chemicals?

Propanoic acid, 2-methyl-, 1-methyl-1-(4-methyl-3-cyclohexen-1-yl)ethyl ester also appears in cosmetics, pharmaceutical, food safety databases.