Is Terpinyl Isobutyrate safe in cosmetics?
Terpinyl Isobutyrate has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.
Excellent
Cosmetic Ingredient
Terpinyl Isobutyrate
INCI: TERPINYL ISOBUTYRATE
Terpinyl Isobutyrate (CAS 7774-65-4) is a cosmetic cosmetic ingredient functioning as Fragrance / Perfuming agent. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 7774-65-4 →
Auto-generated CPSR Part A draft with source citations
Function
Fragrance / Perfuming agent
Safety Rating
EXCELLENT
Chemistry & Identifiers
IUPAC Name
2-(4-methylcyclohex-3-en-1-yl)propan-2-yl 2-methylpropanoate
InChIKey
SMQUXKIIXFOJKI-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted in cosmetics; FEMA GRAS for flavoring use
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Terpinyl Isobutyrate.
Calculate MoS for your specific formulation with the MoS Calculator.
HRIPT Human Patch Test Studies
1 human repeat insult patch test aggregated from dermatological literature.
| Test Type | N | Sensitized | Dose µg/cm² | NESIL µg/cm² | Potency |
|---|---|---|---|---|---|
| HMT | - | 0 | 6750 | - | - |
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Regulatory (2)
JECFA Number
371
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
TERPINYL ISOBUTYRATE | 1998 | No safety concern at current levels of intake when used as a flavouring agent | TRS 891-JECFA 51/79 | FAS 42-JECFA 51/293
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Regulatory List Membership (3)
IFRA Fragrance Transparency List
FDA Substances Added to Food (EAFUS)
Consumer Product Chemical
Expert Verdict
Expert safety assessment and concern-level summary for Terpinyl Isobutyrate.
Regulatory Flags
fragrance-component
ifra_fragrance
fda_food_additive
jecfa_safe
Chemical Function
Fragrance
Flavouring and nutrient
Regulatory Lists
Europe
IFRA Transparency
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
consumer_product
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL4169675
Frequently Asked Questions
Is Terpinyl Isobutyrate allowed in the EU?
Terpinyl Isobutyrate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Terpinyl Isobutyrate do in cosmetics?
Terpinyl Isobutyrate functions as: Fragrance / Perfuming agent. It is classified as a cosmetic ingredient in our database. CAS number: 7774-65-4.
Is Terpinyl Isobutyrate used outside cosmetics?
Terpinyl Isobutyrate also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Terpinyl Isobutyrate compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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