What is the NOAEL for 2-Propenoic acid, 3-phenyl-, 1-methylethyl ester?
2-Propenoic acid, 3-phenyl-, 1-methylethyl ester has 8 NOAEL studies in the database. The lowest reported value is 6RWC10BDD7 UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
2-Propenoic acid, 3-phenyl-, 1-methylethyl ester
Also known as: 2-09-00-00387, BRN 1908938, Isopropyl 3-phenylpropenoate, 1-Methylethyl 3-phenylpropenoate, 1-Methylethyl 3-phenyl-2-propenoate (+1 more)
CAS 7780-06-5
2-Propenoic acid, 3-phenyl-, 1-methylethyl ester (CAS 7780-06-5) is a chemical substance. Key regulatory status: 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
SOURCE
noael studies public
NOAEL studies
8
SOURCE
chemical inventory jurisdictions
Regulatory lists
3
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
12 fields
Name
2-Propenoic acid, 3-phenyl-, 1-methylethyl ester
CAS Number
7780-06-5
DTXSID
DTXSID3064809
Molecular Formula
C12H14O2
InChI Key
RGACABDFLVLVCT-UHFFFAOYSA-N
Monoisotopic Mass
190.09938
Synonyms
2-09-00-00387BRN 1908938Isopropyl 3-phenylpropenoate1-Methylethyl 3-phenylpropenoate1-Methylethyl 3-phenyl-2-propenoateIsopropylester kyseliny skoricove
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
5 records
FragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
3 records
| List | Keyword | Source |
|---|---|---|
| IFRA Transparency | IFRA | IFRA |
| Europe | European Commission | Fl@vis |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 8 of 8 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 6RWC10BDD7 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 6RWC10BDD7 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 6RWC10BDD7 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 6RWC10BDD7 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| - | % | Incidence of positive responses | Dermal | Human | NTP_ICE_skin_sensitization |
| 4050 | ug/cm2 | Induction dose per skin area | Dermal | Human | NTP_ICE_skin_sensitization |
| >5000 | mg/kg bw | LD50 | oral | Rat | NTP_ICE_acute_oral |
| 3 | unitless | Relative reliability score | Dermal | Human | NTP_ICE_skin_sensitization |
Showing 8 of 8 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include 2-Propenoic acid, 3-phenyl-, 1-methylethyl ester?
2-Propenoic acid, 3-phenyl-, 1-methylethyl ester appears on 3 regulatory/inventory lists including IFRA Transparency, Europe, food_additive; Substances Added to Food (formerly EAFUS) (2/2019). Source: EPA CPDat.
Is 2-Propenoic acid, 3-phenyl-, 1-methylethyl ester used in cosmetics?
Yes, 2-Propenoic acid, 3-phenyl-, 1-methylethyl ester is also indexed as a cosmetic ingredient under the name Isopropyl Cinnamate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 2-Propenoic acid, 3-phenyl-, 1-methylethyl ester come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is 2-Propenoic acid, 3-phenyl-, 1-methylethyl ester used outside industrial chemicals?
2-Propenoic acid, 3-phenyl-, 1-methylethyl ester also appears in cosmetics, cannabis databases.