Moderate Cosmetic Ingredient

Isopropyl Cinnamate

CAS Number
7780-06-5
Function
Flavouring and nutrient; Fragrance
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted — no specific restriction under 21 CFR

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

GHS classified as skin irritant (Category 2) and eye irritant (Category 2A); identified as skin sensitizer with maximum recommended cosmetic formula use approximately 0.03%; photoallergenicity not a concern per UV/Vis evaluation; potential cross-reactivity with other cinnamic derivatives should be considered.

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Concern Level: Moderate

Regulatory Flags

potential-allergen fragrance-component ifra_fragrance fda_food_additive jecfa_safe

Frequently Asked Questions

Is Isopropyl Cinnamate safe in cosmetics?

GHS classified as skin irritant (Category 2) and eye irritant (Category 2A); identified as skin sensitizer with maximum recommended cosmetic formula use approximately 0.03%; photoallergenicity not a concern per UV/Vis evaluation; potential cross-reactivity with other cinnamic derivatives should be considered. The EU classifies Isopropyl Cinnamate as "permitted". Safety rating: MODERATE.

Is Isopropyl Cinnamate allowed in the EU?

Isopropyl Cinnamate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Isopropyl Cinnamate do in cosmetics?

Isopropyl Cinnamate functions as: Flavouring and nutrient; Fragrance. It is classified as a cosmetic ingredient in our database. CAS number: 7780-06-5.

What is the Margin of Safety for Isopropyl Cinnamate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check Isopropyl Cinnamate compliance across multiple jurisdictions:

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Ingredient Decoder
Paste a full ingredient list for instant analysis
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82 Allergen Checker
Check for EU declarable fragrance allergens
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Substance Compliance
Check compliance across 55 jurisdictions
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
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Heavy Metal Limits
Compare limits across jurisdictions

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