What is the NOAEL for Magnesium chloride?
Magnesium chloride has 22 NOAEL studies in the database. The lowest reported value is 59XN63C8VM UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Magnesium chloride
Also known as: Magnesium chloride anhydrous, Magnesium chloride (MgCl2), Caswell No. 531, DUS-top, EINECS 232-094-6 (+5 more)
CAS 7786-30-3
Magnesium chloride (CAS 7786-30-3) is a chemical substance. Key regulatory status: REACH registered, 29 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH, ILO ICSC.
View cosmetic safety profile for Bischofite Magnesium Chloride →
Cross-Vertical Regulatory Divergence
Magnesium chloride is classified GHS Danger (H290, H302, H315, H318, H319, H335) in the chemicals database but is allowed in EU cosmetics.
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
SOURCE
noael studies public
NOAEL studies
22
SOURCE
chemical inventory jurisdictions
Regulatory lists
29
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
16 fields
Name
Magnesium chloride
CAS Number
7786-30-3
DTXSID
DTXSID5034690
Molecular Formula
2ClH.Mg
InChI Key
TWRXJAOTZQYOKJ-UHFFFAOYSA-L
Monoisotopic Mass
95.938397
Synonyms
Magnesium chloride anhydrousMagnesium chloride (MgCl2)Caswell No. 531DUS-topEINECS 232-094-6EPA Pesticide Chemical Code 013902UNII-59XN63C8VMMgCl2[MgCl2]Magnesium chloride, anhydrous
ICSC Chemical Safety
International Chemical Safety Card hazard and exposure summary.
SOURCE
ILO/WHO International Chemical Safety Cards
1 records
| Field | Value |
|---|---|
| GHS Signal Word | WARNING |
| GHS Hazard Statements | May be harmful if swallowed |
| Short-term Effects | The substance is mildly irritating to the eyes and respiratory tract. |
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
60 records
Viscosity modifierThickening agentBiocideNo specific technical functionProcessing aids not otherwise specifiedFragranceFiller
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
29 records
| List | Keyword | Source |
|---|---|---|
| drinking_water; Europe; manufacturing; plastic_additive | Belgaqua | CPCat |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | State of California | State of California |
| active_ingredient; Pesticides | California Department of Pesticide Regulation | State of California |
| inert_ingredient; Pesticides | EPA | CPCat |
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
| active_ingredient; animal_products; Europe; pharmaceutical; residue | EU | CPCat |
| Europe; supplements | EU | CPCat |
| Europe; food_additive; supplements | EU | CPCat |
| children; Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| children; Europe; Personal care - general moisturizing - hand/body lotion | Danish Environmental Protection Agency | Danish EPA |
| children; Europe; Personal care - body hygiene - body wash | Danish Environmental Protection Agency | Danish EPA |
| children; Europe; Personal care - hair styling and care - shampoo | Danish Environmental Protection Agency | Danish EPA |
| children; Europe; Personal care - specialized bath products - bubble bath | Danish Environmental Protection Agency | Danish EPA |
| animal_products | USDA | United States Department of Agriculture (USDA) |
| Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| Canada; pharmaceutical | DrugBank | DrugBank |
| IFRA Transparency | IFRA | IFRA |
| SCIL (9/2019) | USEPA | Safer Chemical Ingredients List |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 22 of 22 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 59XN63C8VM | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 59XN63C8VM | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 59XN63C8VM | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 59XN63C8VM | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =0.00002 | mmol | LOEL | injection | Rat | ToxValDB_ECOTOX |
| =0.00125 | mg | LOEL | injection | Mouse | ToxValDB_ECOTOX |
| =0.0046 | mM | LOEL | oral | Rat | ToxValDB_ECOTOX |
| =2 | % | LOEL | oral | Mouse | ToxValDB_ECOTOX |
| =4.5 | mM/kg | LOEL | injection | Dog | ToxValDB_ECOTOX |
| =5 | % | LOEL | oral | Mouse | ToxValDB_ECOTOX |
| =46.4 | mM | LOEL | oral | Rat | ToxValDB_ECOTOX |
| >=1531 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| >=1600 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| 1840 | mg/kg bw/day | NOAEL | oral | mouse | COSMOS_DB |
| 3532 | mg/kg bw/day | NOAEL | oral | mouse | COSMOS_DB |
| >=11400 | mg/kg bw/day | NOAEL | oral | Mouse | ToxValDB_ECHA_IUCLID |
| >=13830 | mg/kg bw/day | NOAEL | oral | Mouse | ToxValDB_ECHA_IUCLID |
| =0.5 | % | NOEL | oral | Mouse | ToxValDB_ECOTOX |
| =1.25 | % | NOEL | oral | Mouse | ToxValDB_ECOTOX |
| =2 | % | NOEL | oral | Mouse | ToxValDB_ECOTOX |
| =2.5 | % | NOEL | oral | Mouse | ToxValDB_ECOTOX |
| =20 | mg/L | NOEL | oral | Rat | ToxValDB_ECOTOX |
Showing 22 of 22 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Magnesium chloride | 232-094-6 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Minerals
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
MAGNESIUM CHLORIDE ANHYDROUS
ChEMBL Phase
4
Adverse Events
618
Bioactivity
0
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
E511 — ADI: NOT LIMITED mg/kg bw
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Magnesium chloride?
Magnesium chloride appears on 18 regulatory/inventory lists including drinking_water; Europe; manufacturing; plastic_additive, active_ingredient; Pesticides, inert_ingredient; Pesticides, and 15 more. Source: EPA CPDat.
Is Magnesium chloride used in cosmetics?
Yes, Magnesium chloride is also indexed as a cosmetic ingredient under the name Bischofite Magnesium Chloride. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Magnesium chloride come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, ILO/WHO ICSC, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Does Magnesium chloride have different safety status in cosmetics vs industrial chemicals?
Magnesium chloride is classified GHS Danger (H290, H302, H315, H318, H319, H335) in the chemicals database but is allowed in EU cosmetics.
Is Magnesium chloride used outside industrial chemicals?
Magnesium chloride also appears in cosmetics, pharmaceutical, food safety, cannabis databases.