What is the NOAEL for Phenol, 4-(butoxymethyl)-2-methoxy-?
Phenol, 4-(butoxymethyl)-2-methoxy- has 6 NOAEL studies in the database. The lowest reported value is S2ULN37C9R UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Phenol, 4-(butoxymethyl)-2-methoxy-
Also known as: 4-(Butoxymethyl)-2-methoxyphenol, Butyl vanillyl ether, FEMA No. 3796, UNII-S2ULN37C9R
CAS 82654-98-6
Phenol, 4-(butoxymethyl)-2-methoxy- (CAS 82654-98-6) is a chemical substance. Key regulatory status: REACH registered, 5 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
6
SOURCE
chemical inventory jurisdictions
Regulatory lists
5
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
10 fields
Name
Phenol, 4-(butoxymethyl)-2-methoxy-
CAS Number
82654-98-6
DTXSID
DTXSID2072881
Molecular Formula
C12H18O3
InChI Key
VLDFMKOUUQYFGF-UHFFFAOYSA-N
Monoisotopic Mass
210.125594
Synonyms
4-(Butoxymethyl)-2-methoxyphenolButyl vanillyl etherFEMA No. 3796UNII-S2ULN37C9R
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
17 records
DeodorizerSoftener and conditionerFragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
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EPA CPDat
5 records
| List | Keyword | Source |
|---|---|---|
| Europe | European Commission | Fl@vis |
| Europe | European Commission | Fl@vis |
| IFRA Transparency | IFRA | IFRA |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| Canada; pharmaceutical | DrugBank | DrugBank |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 6 of 6 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| S2ULN37C9R | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| S2ULN37C9R | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| S2ULN37C9R | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| S2ULN37C9R | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =150 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =600 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
Showing 6 of 6 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | 4-(butoxymethyl)-2-methoxyphenol | 444-010-7 | ECHA overview → |
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
ADI: No safety concern at current levels of intake when used as a flavouring agent mg/kg bw
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Phenol, 4-(butoxymethyl)-2-methoxy-?
Phenol, 4-(butoxymethyl)-2-methoxy- appears on 4 regulatory/inventory lists including Europe, IFRA Transparency, food_additive; Substances Added to Food (formerly EAFUS) (2/2019), and 1 more. Source: EPA CPDat.
Is Phenol, 4-(butoxymethyl)-2-methoxy- used in cosmetics?
Yes, Phenol, 4-(butoxymethyl)-2-methoxy- is also indexed as a cosmetic ingredient under the name Vanillyl Butyl Ether. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Phenol, 4-(butoxymethyl)-2-methoxy- come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is Phenol, 4-(butoxymethyl)-2-methoxy- used outside industrial chemicals?
Phenol, 4-(butoxymethyl)-2-methoxy- also appears in cosmetics, food safety, cannabis databases.