Also known as: 2-[(3-amino-4-methoxyphenyl)amino]ethanol sulfate
CAS 83763-48-8
Ethanol, 2-[(3-amino-4-methoxyphenyl)amino]-, sulfate (1:1) (CAS 83763-48-8) is a chemical substance. Key regulatory status: REACH registered, 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, SCCS, ECHA REACH.
View cosmetic safety profile for 2-Amino-4-Hydroxyethylaminoanisole Sulfate →
Ethanol, 2-[(3-amino-4-methoxyphenyl)amino]-, sulfate (1:1) is prohibited in EU cosmetics at max 1.5% but has active industrial GHS classifications (H302, H315, H317, H319, H373, H400, H410, H411).
CAS, identifiers, formula, and alternate names for the matched substance record.
Industrial and product-use categories associated with this substance.
Inventory, screening, and regulatory list matches from public chemical databases.
| List | Keyword | Source |
|---|---|---|
| Canada; Personal care; Substances in PCP - Canada (4/2014) | Government of Canada | CPCat |
| Europe; Personal care - hair coloring | Danish Environmental Protection Agency | Danish EPA |
Toxicology endpoints rendered from public NOAEL study rows.
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| UM91A54Z8G | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 15 | mg/kg bw/day | LOAEL | oral | rat | COSMOS DB |
| =15 | mg/kg bw/day | NOAEL | oral | Rat | ECHA |
| =30 | mg/kg bw/day | NOAEL | oral | Rat | ECHA |
| >150 | mg/kg bw/day | NOAEL | oral | Rat | ECHA |
| =300 | mg/kg bw/day | NOAEL | dermal | Guinea Pig | ECHA |
Showing 6 of 6 studies
Registration status from the ECHA REACH registered substances database.
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | (3-ammonio-4-methoxyphenyl)(2-hydroxyethyl)ammonium sulphate | 280-734-8 | ECHA overview → |
Australian industrial chemicals inventory status and applicable conditions.
EU Scientific Committee opinions tied to the matched substance.
| Opinion | Date | Conclusion | Max Conc. | Concerns |
|---|---|---|---|---|
| SCCP/1172/08 | 2008-06-24 | In its opinion SCCP/0958/05 of 28 March 2006, the SCCP requested a 'skin penetration test using 2-amino-4-hydroxyethylamino-anisole sulfate and conforming to current Notes of Guidance for Safety Evaluation'. However, the study included in the present submission does not follow these SCCP guidelines. Consequently, opinion SCCP/0958/05 of 28 March 2006 remains unchanged. | - | Submitted skin penetration study does not follow the requested SCCP Notes of Guidance protocol; data insufficient to update the existing opinion. |
Same-CAS cosmetic ingredient record for cross-vertical context.
Ethanol, 2-[(3-amino-4-methoxyphenyl)amino]-, sulfate (1:1) has 6 NOAEL studies in the database. The lowest reported value is UM91A54Z8G UNII. Source: openFDA substances.
Ethanol, 2-[(3-amino-4-methoxyphenyl)amino]-, sulfate (1:1) appears on 2 regulatory/inventory lists including Canada; Personal care; Substances in PCP - Canada (4/2014), Europe; Personal care - hair coloring. Source: EPA CPDat.
Yes, Ethanol, 2-[(3-amino-4-methoxyphenyl)amino]-, sulfate (1:1) is also indexed as a cosmetic ingredient under the name 2-Amino-4-Hydroxyethylaminoanisole Sulfate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.
Ethanol, 2-[(3-amino-4-methoxyphenyl)amino]-, sulfate (1:1) is prohibited in EU cosmetics at max 1.5% but has active industrial GHS classifications (H302, H315, H317, H319, H373, H400, H410, H411).
Ethanol, 2-[(3-amino-4-methoxyphenyl)amino]-, sulfate (1:1) also appears in cosmetics databases.