What is the NOAEL for Hypericum perforatum extract?
Hypericum perforatum extract has 2 NOAEL studies in the database. The lowest reported value is UFH8805FKA UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Hypericum perforatum extract
Also known as: St. John's Wort extract, EINECS 282-026-4, Hypericum oil, hypericum perforatum leaf extract, Hypericum perforatum tincture
CAS 84082-80-4
Hypericum perforatum extract (CAS 84082-80-4) is a chemical substance. Key regulatory status: 6 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
View cosmetic safety profile for Hypericum Perforatum Extract →
SOURCE
NOAEL studies
NOAEL studies
2
SOURCE
Chemical inventory jurisdictions
Regulatory lists
6
SOURCE
EU CLP Annex VI
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
7 fields
Name
Hypericum perforatum extract
CAS Number
84082-80-4
Synonyms
St. John's Wort extractEINECS 282-026-4Hypericum oilhypericum perforatum leaf extractHypericum perforatum tincture
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
53 records
HumectantBiocideAntioxidantAstringentDeodorizerSoftener and conditionerAntiperspirant
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
6 records
| List | Keyword | Source |
|---|---|---|
| Canada; Personal care; Substances in PCP - Canada (4/2014) | Government of Canada | CPCat |
| Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 2 of 2 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| UFH8805FKA | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| concept | identifier | FDA UNII substance identifier | - | - | openFDA substances |
Showing 2 of 2 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
restricted
Max
Concentration limits apply based on hypericin content; specific limit determined by extract hypericin quantification
Category
active
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
ChEMBL / DailyMed
ChEMBL Phase
Not listed
Adverse Events
57
Bioactivity
0
Frequently Asked Questions
What regulatory lists include Hypericum perforatum extract?
Hypericum perforatum extract appears on 2 regulatory/inventory lists including Canada; Personal care; Substances in PCP - Canada (4/2014), Europe; Personal care. Source: EPA CPDat.
Is Hypericum perforatum extract used in cosmetics?
Yes, Hypericum perforatum extract is also indexed as a cosmetic ingredient under the name Hypericum Perforatum Extract. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Hypericum perforatum extract come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Is Hypericum perforatum extract used outside industrial chemicals?
Hypericum perforatum extract also appears in cosmetics, pharmaceutical databases.