What is the NOAEL for Sphingomyelins?
Sphingomyelins has 4 NOAEL studies in the database. The lowest reported value is 25WE4JC35O UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Sphingomyelins
Also known as: Ceramides, 1-(dihydrogen phosphates), monoesters with choline hydroxide, inner salts, Sphingomyelin, Phosphingosides, Phosphatides, sphingosine-contg, Milk Ceramide 4G (+1 more)
CAS 85187-10-6
Sphingomyelins (CAS 85187-10-6) is a chemical substance. Key regulatory status: 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
3
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
9 fields
Name
Sphingomyelins
CAS Number
85187-10-6
DTXSID
DTXSID001021895
Synonyms
Ceramides, 1-(dihydrogen phosphates), monoesters with choline hydroxide, inner saltsSphingomyelinPhosphingosidesPhosphatides, sphingosine-contgMilk Ceramide 4GCeramide BT
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
1 records
Softener and conditioner
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
3 records
| List | Keyword | Source |
|---|---|---|
| Canada | - | https://www.canada.ca/en/health-canada/services/environmental-workplace-health/environmental-contaminants/drugs-personal-care-products/environmental-impact-initiative/commerce-list-food-drugs-act-substances/substances-cosmetics-personal-care-products-regulated-under-food-drugs-act-that-were-commerce-between-january-1-1987-september-13-2001-cas-registry.html |
| Personal care | - | https://www.canada.ca/en/health-canada/services/environmental-workplace-health/environmental-contaminants/drugs-personal-care-products/environmental-impact-initiative/commerce-list-food-drugs-act-substances/substances-cosmetics-personal-care-products-regulated-under-food-drugs-act-that-were-commerce-between-january-1-1987-september-13-2001-cas-registry.html |
| Substances in PCP - Canada (4/2014) | - | https://www.canada.ca/en/health-canada/services/environmental-workplace-health/environmental-contaminants/drugs-personal-care-products/environmental-impact-initiative/commerce-list-food-drugs-act-substances/substances-cosmetics-personal-care-products-regulated-under-food-drugs-act-that-were-commerce-between-january-1-1987-september-13-2001-cas-registry.html |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 25WE4JC35O | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 25WE4JC35O | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 25WE4JC35O | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 25WE4JC35O | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Emollient
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA / FDA GRAS
1 records
FDA GRAS: FDA has no questions
View full food safety profile →Frequently Asked Questions
What regulatory lists include Sphingomyelins?
Sphingomyelins appears on 3 regulatory/inventory lists including Canada, Personal care, Substances in PCP - Canada (4/2014). Source: EPA CPDat.
Is Sphingomyelins used in cosmetics?
Yes, Sphingomyelins is also indexed as a cosmetic ingredient under the name Sphingomyelin. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Sphingomyelins come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, EFSA / FDA GRAS. All data traces to primary regulatory sources and is updated from official government databases.
Is Sphingomyelins used outside industrial chemicals?
Sphingomyelins also appears in cosmetics, food safety databases.