Is Sphingomyelin safe in cosmetics?
Sphingomyelin has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.
Excellent
Cosmetic Ingredient
Sphingomyelin
Also known as: Ceramides, 1-(dihydrogen phosphates), monoesters with choline hydroxide, inner salts, Phosphingosides, Phosphatides, sphingosine-contg, Milk Ceramide 4G, Ceramide BT
INCI: SPHINGOMYELIN
Sphingomyelin (CAS 85187-10-6) is a cosmetic cosmetic ingredient functioning as Skin conditioning, emollient; major component of cell membrane lipid bilayer;. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 85187-10-6 →
Auto-generated CPSR Part A draft with source citations
Function
Skin conditioning, emollient; major component of cell membrane lipid bilayer; supports barrier function
Safety Rating
EXCELLENT
Chemistry & Identifiers
IUPAC Name
2-[[(E,2S,3R)-2-formamido-3-hydroxyoctadec-4-enoxy]-hydroxyphosphoryl]oxyethyl-trimethylazanium
InChIKey
LRYZPFWEZHSTHD-HEFFAWAOSA-O
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted; CIR assessed within the ceramide family as "safe as used"; also reviewed within the lecithin/phospholipid safety assessment
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Sphingomyelin.
Calculate MoS for your specific formulation with the MoS Calculator.
Additional Ingredient Properties
1 property record from structured ingredient metadata.
emulsion_hlb
{"hlb_required_as_emulsifier": "yes", "emulsifier_type": "w_o", "critical_packing_parameter": "0.55-0.75", "emulsion_stabilization_mechanism": "electrostatic_steric", "co_emulsifier_pairs": "cholesterol", "optimal_oil_phase_pct": "60-85", "optimal_water_phase_pct": "15-40", "electrolyte_tolerance": "moderate", "pH_emulsion_stability_range": "5.0-8.5", "viscosity_building_contribution": "low", "dro…
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Softener and conditioner
Expert Verdict
Expert safety assessment and concern-level summary for Sphingomyelin.
Regulatory Flags
potential-allergen
natural-origin
Known Synonyms
Ceramides, 1-(dihydrogen phosphates), monoesters with choline hydroxide, inner salts
Phosphingosides
Phosphatides, sphingosine-contg
Milk Ceramide 4G
Ceramide BT
Chemical Function
Softener and conditioner
Regulatory Lists
Canada
Personal care
Substances in PCP - Canada (4/2014)
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Sphingomyelin allowed in the EU?
Sphingomyelin EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Sphingomyelin do in cosmetics?
Sphingomyelin functions as: Skin conditioning, emollient; major component of cell membrane lipid bilayer; supports barrier function. It is classified as a cosmetic ingredient in our database. CAS number: 85187-10-6.
Compliance Tools
Check Sphingomyelin compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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