Is Sphingomyelin safe in cosmetics?
Sphingomyelin has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.
EXCELLENT
Cosmetic Ingredient
Sphingomyelin
Also known as: Ceramides, 1-(dihydrogen phosphates), monoesters with choline hydroxide, inner salts, Phosphingosides, Phosphatides, sphingosine-contg, Milk Ceramide 4G, Ceramide BT
INCI: SPHINGOMYELIN
Sphingomyelin (CAS 85187-10-6) is a cosmetic cosmetic ingredient functioning as Skin conditioning, emollient; major component of cell membrane lipid bilayer;. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in food safety data.
View industrial chemical safety profile for CAS 85187-10-6 →
Function
Skin conditioning, emollient; major component of cell membrane lipid bilayer; supports barrier function
Editorial assessment
EXCELLENT
Preliminary editorial note — not a computed safety verdict.
Chemistry & Identifiers
IUPAC Name
2-[[(E,2S,3R)-2-formamido-3-hydroxyoctadec-4-enoxy]-hydroxyphosphoryl]oxyethyl-trimethylazanium
InChIKey
LRYZPFWEZHSTHD-HEFFAWAOSA-O
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted; CIR assessed within the ceramide family as "safe as used"; also reviewed within the lecithin/phospholipid safety assessment
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Sphingomyelin.
Calculate MoS for your specific formulation with the MoS Calculator.
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Softener and conditioner
Editorial summary
Preliminary editorial summary for Sphingomyelin — not a computed safety verdict. See the sourced toxicological data above.
Regulatory Flags
potential-allergen
natural-origin
Known Synonyms
Ceramides, 1-(dihydrogen phosphates), monoesters with choline hydroxide, inner salts
Phosphingosides
Phosphatides, sphingosine-contg
Milk Ceramide 4G
Ceramide BT
Chemical Function
Softener and conditioner
Regulatory Lists
Canada
Personal care
Substances in PCP - Canada (4/2014)
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in food safety data.
SOURCE
EFSA / FDA GRAS
fda_gras_enriched
Food Safety Data
Same-CAS food additive or FDA GRAS records from the core public database.
Food Name
Glycolipids from Dacryopinax spathularia
FDA GRAS
FDA has no questions
GRN
740
For use as an antimicrobial agent in select non-alcoholic beverages at use levels ranging from 2 to 100 ppm, and as an antimicrobial agent on cheese (all types) and dry-cured sausage (including sausage casings prior to filling and dry-curing) at levels...
View full food safety profile →Frequently Asked Questions
Is Sphingomyelin allowed in the EU?
Sphingomyelin EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Sphingomyelin do in cosmetics?
Sphingomyelin functions as: Skin conditioning, emollient; major component of cell membrane lipid bilayer; supports barrier function. It is classified as a cosmetic ingredient in our database. CAS number: 85187-10-6.
Is Sphingomyelin used outside cosmetics?
Sphingomyelin also appears in food safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Sphingomyelin compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
Related Ingredients
Acacia Decurrens/Jojoba/Sunflower Seed Wax Polyglyceryl-3 Esters
EXCELLENT
Same category
Skin conditioning emollient, texturizer
Acetic/Linoleic/Palmitic Triglyceride
EXCELLENT
Same category
Skin conditioning (emollient)
Acetyl Ornithine
EXCELLENT
Same category
Emollient
Acetyl Proline
EXCELLENT
Same category
Emollient
Acetyl Triethylhexyl Citrate
EXCELLENT
Same category
Emollient, Film Forming, Plasticiser
Acetyl Trihexyl Citrate
EXCELLENT
Same category
Plasticiser, Skin Conditioning (Emoll...
1-Methylhydantoin-2-imide (Creatinine)
EXCELLENT
Similar safety
Skin conditioning (skin brightening/l...
2,6-Dimethyl-7-octen-2-ol (Dihydromyrcenol)
EXCELLENT
Similar safety
Fragrance (perfuming), masking
2-Ethoxy-2,6,6-Trimethyl-9-Methylenebicyclo[3.3.1]Nonane (Boisiris™)
EXCELLENT
Similar safety
Fragrance (rich woody, orris/iris roo...
2-Hydroxypropylcarbamato Amodimethicone
EXCELLENT
Similar safety
Hair conditioning; modified aminosili...
2-O-Ethyl Ascorbic Acid
EXCELLENT
Similar safety
Softener and conditioner
3 O Ethyl Ascorbic Acid
EXCELLENT
Similar safety
Antioxidant; tyrosinase inhibitor; me...
CASSIA ANGUSTIFOLIA LEAF EXTRACT
GOOD
Chemical family
Skin Conditioning
Cassia Angustifolia Seed Extract
MODERATE
Chemical family
Skin Conditioning
Cassia Angustifolia Seed Polysaccharide
EXCELLENT
Chemical family
Skin conditioning agent; film-forming...
Is Sphingomyelin in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Sphingomyelin in your formulation.