What is the NOAEL for Dipropyleneglycol methyl ether acetate?
Dipropyleneglycol methyl ether acetate has 7 NOAEL studies in the database. The lowest reported value is 1556 mg/m3 via inhalation in Human. Source: ToxValDB_GESTIS_DNEL.
NOAEL Data
REACH Registered
Cosmetic Ingredient
Dipropyleneglycol methyl ether acetate
Also known as: Propanol, 1(or 2)-(2-methoxymethylethoxy)-, acetate, DPMA (solvent), DPMA acetate, Dowanol DPMA, Arcosolv DPMA (+5 more)
CAS 88917-22-0
Dipropyleneglycol methyl ether acetate (CAS 88917-22-0) is a chemical substance. Key regulatory status: REACH registered, 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH, ILO ICSC.
View cosmetic safety profile for PPG-2 Methyl Ether Acetate →
SOURCE
noael studies public
NOAEL studies
7
SOURCE
chemical inventory jurisdictions
Regulatory lists
3
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
13 fields
Name
Dipropyleneglycol methyl ether acetate
CAS Number
88917-22-0
DTXSID
DTXSID4029062
Synonyms
Propanol, 1(or 2)-(2-methoxymethylethoxy)-, acetateDPMA (solvent)DPMA acetateDowanol DPMAArcosolv DPMADipropylene glycol monomethyl ether acetateACETATE, 1(OR 2)-(2-METHOXYMETHYL-ETHOXY)-, PROPYL1(or 2)-(2-Methoxymethylethoxy)propanol acetateEC No.: 618-219-0UNII-5455FZE9RB
ICSC Chemical Safety
International Chemical Safety Card hazard and exposure summary.
SOURCE
ILO/WHO International Chemical Safety Cards
1 records
| Field | Value |
|---|---|
| GHS Signal Word | WARNING |
| GHS Hazard Statements | Combustible liquid May be fatal if swallowed and enters airways |
| Short-term Effects | If swallowed the substance may cause vomiting and could result in aspiration pneumonitis. |
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
60 records
SolventFragrance
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
3 records
| List | Keyword | Source |
|---|---|---|
| SCIL (9/2019) | USEPA | Safer Chemical Ingredients List |
| IFRA Transparency | IFRA | IFRA |
| consumer_product | P&G | Proctor & Gamble |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 7 of 7 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| =1556 | mg/m3 | DNEL systemic | inhalation | Human | ToxValDB_GESTIS_DNEL |
| 5455FZE9RB | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 5455FZE9RB | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 5455FZE9RB | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 5455FZE9RB | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =1000 | mg/kg bw/day | NOAEL | oral | Rat | ToxValDB_ECHA_IUCLID |
| =250 | mg/kg bw/day | NOEL | oral | Rat | ToxValDB_ECHA_IUCLID |
Showing 7 of 7 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | A mixture of RR and RS isomers of: (2-(2-methoxy-1-methyl)ethoxy)-1-methylethyl acetate; (2-(2-methoxy-2-methyl)ethoxy)-1-methylethyl acetate; (2-(2-methoxy-2-methyl)ethoxy)-2-methylethyl acetate; (2-(2-methoxy-1-methyl)ethoxy)-2-methylethyl acetate | 406-880-6 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL1255792
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Frequently Asked Questions
What regulatory lists include Dipropyleneglycol methyl ether acetate?
Dipropyleneglycol methyl ether acetate appears on 3 regulatory/inventory lists including SCIL (9/2019), IFRA Transparency, consumer_product. Source: EPA CPDat.
Is Dipropyleneglycol methyl ether acetate used in cosmetics?
Yes, Dipropyleneglycol methyl ether acetate is also indexed as a cosmetic ingredient under the name PPG-2 Methyl Ether Acetate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Dipropyleneglycol methyl ether acetate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, ILO/WHO ICSC, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Is Dipropyleneglycol methyl ether acetate used outside industrial chemicals?
Dipropyleneglycol methyl ether acetate also appears in cosmetics, pharmaceutical databases.