What is the NOAEL for Menthyl salicylate?
Menthyl salicylate has 4 NOAEL studies in the database. The lowest reported value is 43XOA705ZD UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Menthyl salicylate
Also known as: (1R,2S,5R)-5-Methyl-2-(propan-2-yl)cyclohexyl 2-hydroxybenzoate, Benzoic acid, 2-hydroxy-, (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester, EINECS 201-909-7, 1-Menthyl salicylate, UNII-43XOA705ZD
CAS 89-46-3
Menthyl salicylate (CAS 89-46-3) is a chemical substance. Key regulatory status: 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
3
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
11 fields
Name
Menthyl salicylate
CAS Number
89-46-3
DTXSID
DTXSID8046822
Molecular Formula
C17H24O3
InChI Key
SJOXEWUZWQYCGL-DVOMOZLQSA-N
Monoisotopic Mass
276.172545
Synonyms
(1R,2S,5R)-5-Methyl-2-(propan-2-yl)cyclohexyl 2-hydroxybenzoateBenzoic acid, 2-hydroxy-, (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl esterEINECS 201-909-71-Menthyl salicylateUNII-43XOA705ZD
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
3 records
UV stabilizerDeodorizerFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
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EPA CPDat
3 records
| List | Keyword | Source |
|---|---|---|
| Canada; Personal care; Substances in PCP - Canada (4/2014) | Government of Canada | CPCat |
| Europe | European Commission | Fl@vis |
| Canada; pharmaceutical | DrugBank | DrugBank |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 43XOA705ZD | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 43XOA705ZD | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 43XOA705ZD | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 43XOA705ZD | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
restricted
Max
-
Category
Fragrance
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
menthyl salicylate
ChEMBL Phase
Not listed
Adverse Events
15
Bioactivity
0
Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Menthyl salicylate?
Menthyl salicylate appears on 3 regulatory/inventory lists including Canada; Personal care; Substances in PCP - Canada (4/2014), Europe, Canada; pharmaceutical. Source: EPA CPDat.
Is Menthyl salicylate used in cosmetics?
Yes, Menthyl salicylate is also indexed as a cosmetic ingredient under the name Menthyl Salicylate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Menthyl salicylate come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is Menthyl salicylate used outside industrial chemicals?
Menthyl salicylate also appears in cosmetics, pharmaceutical, cannabis databases.