Menthyl Salicylate

Also known as: (1R,2S,5R)-5-Methyl-2-(propan-2-yl)cyclohexyl 2-hydroxybenzoate, Benzoic acid, 2-hydroxy-, (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester, EINECS 201-909-7, 1-Menthyl salicylate, UNII-43XOA705ZD

INCI: MENTHYL SALICYLATE

Menthyl Salicylate (CAS 89-46-3) is a cosmetic cosmetic ingredient functioning as Fragrance ingredient, UV absorber. EU Regulation 1223/2009 status: restricted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.

View industrial chemical safety profile for CAS 89-46-3 →

Auto-generated CPSR Part A draft with source citations
Function
Fragrance ingredient, UV absorber
Safety Rating
MODERATE

Chemistry & Identifiers

Formula
C17H24O3
MW
276.4 g/mol
PubChem CID
20055232
IUPAC Name
[(1R,2S,5R)-5-methyl-2-propan-2-ylcyclohexyl] 2-hydroxybenzoate
InChIKey
SJOXEWUZWQYCGL-DVOMOZLQSA-N

Regulatory Status

EU EU Status restricted
US US Status permitted
US Notes Allowed in cosmetics; not listed as a prohibited or restricted ingredient. Not an approved OTC sunscreen active despite UV-absorbing properties.

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Menthyl Salicylate.

Calculate MoS for your specific formulation with the MoS Calculator.

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Deodorizer Flavouring and nutrient UV stabilizer

Expert Verdict

Expert safety assessment and concern-level summary for Menthyl Salicylate.

Regulatory Flags

potential-allergen fragrance-component

Known Synonyms

(1R,2S,5R)-5-Methyl-2-(propan-2-yl)cyclohexyl 2-hydroxybenzoate Benzoic acid, 2-hydroxy-, (1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl ester EINECS 201-909-7 1-Menthyl salicylate UNII-43XOA705ZD

Chemical Function

UV stabilizer Deodorizer Flavouring and nutrient

Regulatory Lists

Canada; Personal care; Substances in PCP - Canada (4/2014) Europe Canada; pharmaceutical

Australian Status

AICIS status: listed

Cross-Vertical Safety Context

Same-CAS public records found in pharmaceutical data.

SOURCE ChEMBL / DrugCentral / FAERS DB_PHARMA CAS match

Pharmaceutical Data

Same-CAS rows from the pharmaceutical spoke database.

Compound
menthyl salicylate
Adverse Event Associations
15
View full pharmaceutical profile →

Frequently Asked Questions

Is Menthyl Salicylate safe in cosmetics?

Menthyl Salicylate has a safety rating of "MODERATE" in our database. EU status: restricted. US status: permitted.

Is Menthyl Salicylate allowed in the EU?

Menthyl Salicylate EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does Menthyl Salicylate do in cosmetics?

Menthyl Salicylate functions as: Fragrance ingredient, UV absorber. It is classified as a cosmetic ingredient in our database. CAS number: 89-46-3.

Is Menthyl Salicylate used outside cosmetics?

Menthyl Salicylate also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.

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