What is the NOAEL for Guar gum?
Guar gum has 26 NOAEL studies in the database. The lowest reported value is E89I1637KE UNII. Source: openFDA substances.
NOAEL Data
Cosmetic Ingredient
Guar gum
Also known as: α-D-galacto-β-D-Mannan, α-D-Galactopyrano-β-D-mannopyranan, Burtonite V-7-E, EINECS 232-536-8, FEMA No. 2537 (+10 more)
CAS 9000-30-0
Guar gum (CAS 9000-30-0) is a chemical substance. Key regulatory status: 10 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
View cosmetic safety profile for Cyamopsis Tetragonoloba (Guar) Gum →
SOURCE
NOAEL studies
NOAEL studies
26
SOURCE
Chemical inventory jurisdictions
Regulatory lists
10
SOURCE
EU CLP Annex VI
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
17 fields
Name
Guar gum
CAS Number
9000-30-0
Synonyms
α-D-galacto-β-D-Mannanα-D-Galactopyrano-β-D-mannopyrananBurtonite V-7-EEINECS 232-536-8FEMA No. 2537Guar gum (Cyamopsis tetragonolobus (L.))Jaguar A 20 BJaguar gum A-20-DJaguar No.124Jaguar plusNCI-C50395Supercol G.F.
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
60 records
Film formerAntioxidantDeodorizerSoftener and conditionerViscosity modifierEmulsifierBinderStabilizing agentThickening agentFragranceFlavouring and nutrientPharmaceutical
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
SOURCE
EPA CPDat
10 records
| List | Keyword | Source |
|---|---|---|
| active_ingredient; Pesticides | California Department of Pesticide Regulation | State of California |
| inert_ingredient; Pesticides | EPA | CPCat |
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
| Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| fracking | FracFocus | FracFocus |
| SCIL (9/2019) | USEPA | Safer Chemical Ingredients List |
| Canada; pharmaceutical | DrugBank | DrugBank |
| fracking; water | NY Department of Conservation | CPCat |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 26 of 26 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| E89I1637KE | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| =6770 | mg/kg bw | LD50 | oral | Rat | NTP ICE acute oral |
| =9400 | mg/kg bw | LD50 | oral | Rat | NTP ICE acute oral |
| =0 | ppm | NOAEL | oral | rat | CIR Safety Assessment |
| =1 | g/kg/d | NOAEL | oral | rat | CIR Safety Assessment |
| 200 | mg/kg bw/day | NOAEL | oral | monkey | COSMOS DB |
| 500 | mg/kg bw/day | NOAEL | oral | rat | COSMOS DB |
| 600 | mg/kg bw/day | NOAEL | oral | hamster | COSMOS DB |
| 700 | mg/kg bw/day | NOAEL | oral | rabbit | COSMOS DB |
| 800 | mg/kg bw/day | NOAEL | oral | mouse | COSMOS DB |
| 900 | mg/kg bw/day | NOAEL | oral | rat | COSMOS DB |
| =1000 | mg/kg body weight | NOAEL | oral | rat | CIR Safety Assessment |
| 2500 | mg/kg bw/day | NOAEL | oral | rat | COSMOS DB |
| =2500 | mg/kg bw/day | NOAEL | - | Rat | EFSA |
| 4000 | mg/kg bw/day | NOAEL | oral | swine | COSMOS DB |
| 5000 | mg/kg bw/day | NOAEL | oral | rat | COSMOS DB |
| 5770 | mg/kg bw/day | NOAEL | oral | rat | COSMOS DB |
| 6000 | mg/kg bw/day | NOAEL | oral | rat | COSMOS DB |
| 7500 | mg/kg bw/day | NOAEL | oral | mouse | COSMOS DB |
| 1.000e+4 | mg/kg bw/day | NOAEL | oral | rat | COSMOS DB |
| 1.176e+4 | mg/kg bw/day | NOAEL | oral | rat | COSMOS DB |
| 1.500e+4 | mg/kg bw/day | NOAEL | oral | mouse | COSMOS DB |
| 5.000e+4 | ppm | Top dose | Dosed feed | Mouse | NTP ICE cancer |
| 0 | ppm | developmental toxicity | oral | rat | Regulatory source |
| 1000 | mg/kg body weight | developmental toxicity | oral | rat | Regulatory source |
| 1 | g/kg/d | repeated dose toxicity | oral | rat | Regulatory source |
Showing 26 of 26 studies
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
SOURCE
AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
restricted
Max
-
Category
sunscreen
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
ChEMBL / DailyMed
ChEMBL Phase
Not listed
Adverse Events
302
Bioactivity
0
Food Safety Data
Same-CAS food additive, ADI, and GRAS records where available.
SOURCE
EFSA
1 records
ADI: NOT SPECIFIED mg/kg bw
View full food safety profile →Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include Guar gum?
Guar gum appears on 9 regulatory/inventory lists including active_ingredient; Pesticides, inert_ingredient; Pesticides, inert_ingredient; non_food_use; Pesticides, and 6 more. Source: EPA CPDat.
Is Guar gum used in cosmetics?
Yes, Guar gum is also indexed as a cosmetic ingredient under the name Cyamopsis Tetragonoloba (Guar) Gum. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for Guar gum come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed, EFSA / FDA GRAS, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is Guar gum used outside industrial chemicals?
Guar gum also appears in cosmetics, pharmaceutical, food safety, cannabis databases.