Cyamopsis Tetragonoloba (Guar) Gum
INCI: CYAMOPSIS TETRAGONOLOBA (GUAR) GUM
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
10 study endpoints found for Cyamopsis Tetragonoloba (Guar) Gum. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 2500 mg/kg bw/day | oral | rat | Special Toxicology Study | COSMOS_DB |
| NOAEL | 2500 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
| NOAEL | 700 mg/kg bw/day | oral | rabbit | Developmental | COSMOS_DB |
| NOAEL | 500 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
| NOAEL | 200 mg/kg bw/day | oral | monkey | Subchronic | COSMOS_DB |
| NOAEL | 800 mg/kg bw/day | oral | mouse | Developmental | COSMOS_DB |
| NOAEL | 900 mg/kg bw/day | oral | rat | Developmental | COSMOS_DB |
| NOAEL | 600 mg/kg bw/day | oral | hamster | Developmental | COSMOS_DB |
| NOAEL | 10000 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
| NOAEL | 15000 mg/kg bw/day | oral | mouse | Subchronic | COSMOS_DB |
Safety Opinions
Official safety assessments from the Scientific Committee on Consumer Safety (SCCS) and Cosmetic Ingredient Review (CIR).
netration of these ingredients would be unlikely. The Panel concluded that these galactomannans are safe in the present practices of use and concentration described in this safety assessment. Keywords galactomannans, safety, cosmetics Introduction As given in the International Cosmetic Ingredient Dictio
netration of these ingredients would be unlikely. The Panel concluded that these galactomannans are safe in the present practices of use and concentration described in this safety assessment. Keywords galactomannans, safety, cosmetics Introduction As given in the International Cosmetic Ingredient Dictio
Expert Verdict
Guar gum is a safe thickening and stabilizing agent with good safety profile; restricted in EU under Annex III with concentration limits.
Regulatory Flags
Frequently Asked Questions
Is Cyamopsis Tetragonoloba (Guar) Gum safe in cosmetics?
Guar gum is a safe thickening and stabilizing agent with good safety profile; restricted in EU under Annex III with concentration limits. The EU classifies Cyamopsis Tetragonoloba (Guar) Gum as "restricted". Safety rating: GOOD. 10 toxicological study endpoint(s) are available in our database. This ingredient has been reviewed by cir.
Is Cyamopsis Tetragonoloba (Guar) Gum allowed in the EU?
Cyamopsis Tetragonoloba (Guar) Gum EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.
What does Cyamopsis Tetragonoloba (Guar) Gum do in cosmetics?
Cyamopsis Tetragonoloba (Guar) Gum functions as: Thickening agent, stabilizer. It is classified as a UV Filter / Sunscreen in our database. CAS number: 9000-30-0.
What is the Margin of Safety for Cyamopsis Tetragonoloba (Guar) Gum?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Cyamopsis Tetragonoloba (Guar) Gum?
The NOAEL (No Observed Adverse Effect Level) for Cyamopsis Tetragonoloba (Guar) Gum is 2500 mg/kg bw/day based on a Special Toxicology Study study via oral route in rat. A total of 10 study endpoints are available. Source: COSMOS_DB.
Compliance Tools
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Related Ingredients
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