Danger GHS07GHS08 Cosmetic Ingredient

Ficin

Also known as: Debricin, EINECS 232-599-1, Ficus protease, Ficus proteinase, Higueroxyl delabarre

CAS 9001-33-6

Ficin (CAS 9001-33-6) is a chemical substance with GHS signal word Danger; key hazard signal: H335; H315; H319; H334. Key regulatory status: 2 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from ECHA CLP, EPA CPDat.

View cosmetic safety profile for Ficin →

SOURCE noael studies public
NOAEL studies
0
SOURCE chemical inventory jurisdictions
Regulatory lists
2
SOURCE eu clp annex vi
GHS signal
Danger

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 8 fields
Name
Ficin
CAS Number
9001-33-6
DTXSID
DTXSID3093787
Synonyms
DebricinEINECS 232-599-1Ficus proteaseFicus proteinaseHigueroxyl delabarre

GHS / CLP Classification

EU harmonized hazard classification, hazard statements, pictograms, and signal word.

SOURCE EU CLP Annex VI (ECHA) 1 classifications
Hazard ClassH-StatementsPictogramsSignal
STOT SE 3; Skin Irrit. 2; Eye Irrit. 2; Resp. Sens. 1H335; H315; H319; H334GHS07; GHS08Danger

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 4 records
Softener and conditionerChemical reaction regulatorProcessing aids not otherwise specified

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 2 records
ListKeywordSource
animal_productsUSDAUnited States Department of Agriculture (USDA)
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)FDAUnited States Food and Drug Administration (FDA)

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Skin Conditioning
View full cosmetic safety profile →

Frequently Asked Questions

What is the GHS hazard classification for Ficin?

Ficin (CAS 9001-33-6) is classified under EU CLP Annex VI as STOT SE 3; Skin Irrit. 2; Eye Irrit. 2; Resp. Sens. 1 with signal word Danger. Hazard statements: H335; H315; H319; H334. Source: EU CLP Annex VI (ECHA).

What regulatory lists include Ficin?

Ficin appears on 2 regulatory/inventory lists including animal_products, food_additive; Substances Added to Food (formerly EAFUS) (2/2019). Source: EPA CPDat.

Is Ficin used in cosmetics?

Yes, Ficin is also indexed as a cosmetic ingredient under the name Ficin. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Ficin come from?

Safety data is sourced from ECHA CLP Annex VI, EPA CPDat, EPA DSSTox, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.

Does Ficin have different safety status in cosmetics vs industrial chemicals?

Ficin is classified GHS Danger (H335, H315, H319, H334) in the chemicals database but is allowed in EU cosmetics.

Is Ficin used outside industrial chemicals?

Ficin also appears in cosmetics databases.