Regulatory Status
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Safety Data
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Expert Verdict
Irritant to skin, eyes, and respiratory tract with cross-reactivity risk to papain and bromelain; concentration-dependent proteolysis can compromise skin barrier; occupational sensitization documented.
Regulatory Flags
Frequently Asked Questions
Is Ficin safe in cosmetics?
Irritant to skin, eyes, and respiratory tract with cross-reactivity risk to papain and bromelain; concentration-dependent proteolysis can compromise skin barrier; occupational sensitization documented. The EU classifies Ficin as "permitted". Safety rating: MODERATE.
Is Ficin allowed in the EU?
Ficin EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Ficin do in cosmetics?
Ficin functions as: Skin conditioning / exfoliating enzyme (cysteine protease, EC 3.4.22.3). It is classified as a cosmetic ingredient in our database. CAS number: 9001-33-6.
What is the Margin of Safety for Ficin?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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