NOAEL Data Cosmetic Ingredient

Hyaluronic acid

Also known as: EINECS 232-678-0, UNII-S270N0TRQY, Viscofill Extra, Hyalo-Oligo, Hyal-Joint (+6 more)

CAS 9004-61-9

Hyaluronic acid (CAS 9004-61-9) is a chemical substance. Key regulatory status: 5 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.

View cosmetic safety profile for Hyaluronic Acid →

SOURCE noael studies public

NOAEL studies

SOURCE chemical inventory jurisdictions

Regulatory lists

SOURCE eu clp annex vi

GHS signal

Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 14 fields

Name

Hyaluronic acid

CAS Number

9004-61-9

DTXSID

DTXSID7046750

Synonyms

EINECS 232-678-0UNII-S270N0TRQYViscofill ExtraHyalo-OligoHyal-JointMacronanJuvederm VolumaJuvedermHyruan PlusHyalorigoHyaluronate

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 29 records

HumectantAnti-static agentSoftener and conditionerThickening agentFlavouring and nutrient

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 5 records

List	Keyword	Source
pharmaceutical	FDA	United States Food and Drug Administration (FDA)
active_ingredient; animal_products; Europe; pharmaceutical; residue	EU	CPCat
Europe; Personal care	Danish Environmental Protection Agency	Danish EPA
Europe; Personal care	Danish Environmental Protection Agency	Danish EPA
Canada; pharmaceutical	DrugBank	DrugBank

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 8 of 8 studies

Value	Unit	Endpoint	Route	Species	Source
B7SG5YV2SI	UNII	FDA UNII substance identifier	-	-	openFDA substances
B7SG5YV2SI	UNII	FDA UNII substance identifier	-	-	openFDA substances
B7SG5YV2SI	UNII	FDA UNII substance identifier	-	-	openFDA substances
B7SG5YV2SI	UNII	FDA UNII substance identifier	-	-	openFDA substances
S270N0TRQY	UNII	FDA UNII substance identifier	-	-	openFDA substances
S270N0TRQY	UNII	FDA UNII substance identifier	-	-	openFDA substances
S270N0TRQY	UNII	FDA UNII substance identifier	-	-	openFDA substances
S270N0TRQY	UNII	FDA UNII substance identifier	-	-	openFDA substances

Showing 8 of 8 studies

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records

Inventory Status

listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB

EU Status

permitted

Max

Pharmaceutical Data

Same-CAS pharmaceutical records from drug and bioactivity sources.

SOURCE EMBL-EBI ChEMBL hyaluronic acid

ChEMBL Phase

Not listed

Adverse Events

445

Bioactivity

View full pharmaceutical profile →

Frequently Asked Questions

What is the NOAEL for Hyaluronic acid?

Hyaluronic acid has 8 NOAEL studies in the database. The lowest reported value is B7SG5YV2SI UNII. Source: openFDA substances.

What regulatory lists include Hyaluronic acid?

Hyaluronic acid appears on 4 regulatory/inventory lists including pharmaceutical, active_ingredient; animal_products; Europe; pharmaceutical; residue, Europe; Personal care, and 1 more. Source: EPA CPDat.

Is Hyaluronic acid used in cosmetics?

Yes, Hyaluronic acid is also indexed as a cosmetic ingredient under the name Hyaluronic Acid. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Hyaluronic acid come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.

Is Hyaluronic acid used outside industrial chemicals?

Hyaluronic acid also appears in cosmetics, pharmaceutical databases.