NOAEL Data Cosmetic Ingredient

Alpha-Sulfo-omega-(dodecyloxy)poly(oxy-1,2-ethanediyl) sodium salt

Also known as: Poly(oxy-1,2-ethanediyl), alpha-sulfo-omega-(dodecyloxy)-, sodium salt (1:1), Sodium dodecylpoly(oxyethylene) sulfate, Dodecyl alcohol, monoether with polyethylene glycol, hydrogen sulfate sodium salt, 81-5B, Abex 18S (+13 more)

CAS 9004-82-4

Alpha-Sulfo-omega-(dodecyloxy)poly(oxy-1,2-ethanediyl) sodium salt (CAS 9004-82-4) is a chemical substance. Key regulatory status: 24 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.

View cosmetic safety profile for Sodium Laureth Sulfate →

SOURCE NOAEL studies
NOAEL studies
12
SOURCE Chemical inventory jurisdictions
Regulatory lists
24
SOURCE EU CLP Annex VI
GHS signal
Not classified

Chemical Identity

CAS, identifiers, formula, and alternate names for the matched substance record.

SOURCE DSSTox identifiers 21 fields
Name
Alpha-Sulfo-omega-(dodecyloxy)poly(oxy-1,2-ethanediyl) sodium salt
CAS Number
9004-82-4
Molecular Formula
C14H30O5S.Na
Synonyms
Poly(oxy-1,2-ethanediyl), alpha-sulfo-omega-(dodecyloxy)-, sodium salt (1:1)Sodium dodecylpoly(oxyethylene) sulfateDodecyl alcohol, monoether with polyethylene glycol, hydrogen sulfate sodium salt81-5BAbex 18SPolyoxy (1,2 ethandiyl) alpha-sulpho-omega- dodecyloxy-, sodium saltPoly(oxy-1,2-ethanediyl), .alpha.-sulfo-.omega.-(dodecyloxy)-, sodium salt (1:1)Sodium lauryl polyoxyethylene ether sulfateConco Sulfate WERewopol NL-2Sodium lauryl sulfate ethoxylateStandapol ES-3

Functional Uses

Industrial and product-use categories associated with this substance.

SOURCE EPA CPDat 60 records
Surfactant (surface active agent)EmulsifierCleaning agentFoamantFragrance

Regulatory Lists

Inventory, screening, and regulatory list matches from public chemical databases.

SOURCE EPA CPDat 24 records
ListKeywordSource
inert_ingredient; PesticidesEPACPCat
IFRA TransparencyIFRAIFRA
inert_ingredient; non_food_use; PesticidesEPACPCat
SCIL (9/2019)USEPASafer Chemical Ingredients List
Europe; Personal care - body hygiene - hand soapDanish Environmental Protection AgencyDanish EPA
children; Europe; Personal careDanish Environmental Protection AgencyDanish EPA
children; Europe; Personal care - body hygiene - body washDanish Environmental Protection AgencyDanish EPA
children; Europe; Personal care - hair styling and care - shampooDanish Environmental Protection AgencyDanish EPA
children; Europe; Personal care - specialized bath products - bubble bathDanish Environmental Protection AgencyDanish EPA
children; Europe; Personal careDanish Environmental Protection AgencyDanish EPA
Europe; Personal careDanish Environmental Protection AgencyDanish EPA
Europe; Personal careDanish Environmental Protection AgencyDanish EPA
Europe; Personal careDanish Environmental Protection AgencyDanish EPA
Cleaning products and household care - laundry and fabric treatment - laundry detergent; EuropeDanish EPADanish EPA
Cleaning products and household care - dishwasher and dishes - automatic dishwashing detergent; EuropeDanish EPADanish EPA
Cleaning products and household care; EuropeDanish EPADanish EPA
children; Europe; Personal careDanish Environmental Protection AgencyDanish EPA
children; Europe; Personal care - hair styling and care - shampooDanish Environmental Protection AgencyDanish EPA
active_ingredient; PesticidesState of CaliforniaState of California
active_ingredient; PesticidesState of CaliforniaState of California
active_ingredient; PesticidesState of CaliforniaState of California
active_ingredient; PesticidesState of CaliforniaState of California
active_ingredient; PesticidesCalifornia Department of Pesticide RegulationState of California
Cleaning products and household care - oven - oven cleaner; EuropeDanish Environmental Protection AgencyDanish EPA

NOAEL Studies

Toxicology endpoints rendered from public NOAEL study rows.

SOURCE NOAEL studies Showing 12 of 12 studies
ValueUnitEndpointRouteSpeciesSource
28.24uMAC50--NTP ICE endocrine
16.9uMACC--NTP ICE endocrine
240minBreakthrough TimeDermal-NTP ICE skin irritation
410Q7WN1BXUNIIFDA UNII substance identifier--openFDA substances
BPV390UAP0UNIIFDA UNII substance identifier--openFDA substances
ZZQ59TY3KGUNIIFDA UNII substance identifier--openFDA substances
=1600mg/kg bwLD50oralRatNTP ICE acute oral
0unitlessModel Score--NTP ICE endocrine
0.00534unitlessModel Score--NTP ICE endocrine
0.0892unitlessModel Score--NTP ICE endocrine
1.8kiloohmsTERDermal-NTP ICE skin irritation
4.8kiloohmsTERDermal-NTP ICE skin irritation

Showing 12 of 12 studies

Australian Status (AICIS)

Australian industrial chemicals inventory status and applicable conditions.

SOURCE AICIS inventory 1 records
Inventory Status
listed

Cosmetic Safety Profile

Same-CAS cosmetic ingredient record for cross-vertical context.

SOURCE CosIng / Ingredients DB
EU Status
permitted
Max
1,4-dioxane process impurity capped at ≤10 ppm per EU GMP guidance
Category
surfactant
View full cosmetic safety profile →

Frequently Asked Questions

What is the NOAEL for Alpha-Sulfo-omega-(dodecyloxy)poly(oxy-1,2-ethanediyl) sodium salt?

Alpha-Sulfo-omega-(dodecyloxy)poly(oxy-1,2-ethanediyl) sodium salt has 12 NOAEL studies in the database. The lowest reported value is 16.9 uM. Source: NTP ICE endocrine.

What regulatory lists include Alpha-Sulfo-omega-(dodecyloxy)poly(oxy-1,2-ethanediyl) sodium salt?

Alpha-Sulfo-omega-(dodecyloxy)poly(oxy-1,2-ethanediyl) sodium salt appears on 15 regulatory/inventory lists including inert_ingredient; Pesticides, IFRA Transparency, inert_ingredient; non_food_use; Pesticides, and 12 more. Source: EPA CPDat.

Is Alpha-Sulfo-omega-(dodecyloxy)poly(oxy-1,2-ethanediyl) sodium salt used in cosmetics?

Yes, Alpha-Sulfo-omega-(dodecyloxy)poly(oxy-1,2-ethanediyl) sodium salt is also indexed as a cosmetic ingredient under the name Sodium Laureth Sulfate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.

Where does the safety data for Alpha-Sulfo-omega-(dodecyloxy)poly(oxy-1,2-ethanediyl) sodium salt come from?

Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB. All data traces to primary regulatory sources and is updated from official government databases.

Does Alpha-Sulfo-omega-(dodecyloxy)poly(oxy-1,2-ethanediyl) sodium salt have different safety status in cosmetics vs industrial chemicals?

Alpha-Sulfo-omega-(dodecyloxy)poly(oxy-1,2-ethanediyl) sodium salt is classified GHS Danger (H315, H318, H319, H412) in the chemicals database but is allowed in EU cosmetics at max 1,4-dioxane process impurity capped at ≤10 ppm per EU GMP guidance.

Is Alpha-Sulfo-omega-(dodecyloxy)poly(oxy-1,2-ethanediyl) sodium salt used outside industrial chemicals?

Alpha-Sulfo-omega-(dodecyloxy)poly(oxy-1,2-ethanediyl) sodium salt also appears in cosmetics databases.