Also known as: Cremophor A, Crill 20,21,22,23, Emcol H 35-A, Empilan CP-100, Empilan CQ-100 (+14 more)
CAS 9004-99-3
Poly(oxy-1,2-ethanediyl), .alpha.-(1-oxooctadecyl)-.omega.-hydroxy- (CAS 9004-99-3) is a chemical substance. Key regulatory status: 16 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS.
CAS, identifiers, formula, and alternate names for the matched substance record.
Industrial and product-use categories associated with this substance.
Inventory, screening, and regulatory list matches from public chemical databases.
| List | Keyword | Source |
|---|---|---|
| children; Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| children; Europe; Personal care - general moisturizing - hand/body lotion | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| Canada; pharmaceutical | DrugBank | DrugBank |
| CEDI | FDA | United States Food and Drug Administration (FDA) |
| Indirect additives food contact (10/2018) | FDA | United States Food and Drug Administration (FDA) |
| children; Europe; Personal care | Danish Environmental Protection Agency | Danish EPA |
| children; Europe; Personal care - general moisturizing - hand/body lotion | Danish Environmental Protection Agency | Danish EPA |
| IFRA Transparency | IFRA | IFRA |
| active_ingredient; Pesticides | California Department of Pesticide Regulation | State of California |
| SCIL (9/2019) | USEPA | Safer Chemical Ingredients List |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| inert_ingredient; Pesticides | EPA | CPCat |
| inert_ingredient; non_food_use; Pesticides | EPA | CPCat |
Toxicology endpoints rendered from public NOAEL study rows.
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 0 | unitless | Draize rabbit irritation score | Ocular | Rabbit | NTP ICE eye irritation |
| 0V73PIX5YC | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 1J2956FWUB | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 1U8KB35S20 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 1X2OAT3BFK | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 2P9L47VI5E | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 33GX5WQC0M | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 3954DT14A6 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 4L5ODS320S | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 569T0R267J | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 5I60X40576 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 5WD387V180 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 776CJK5X56 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 7BSG7DF10Q | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 7TB32G765E | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 8LQC57C6B0 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 9KU38O8CEK | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| D3AHD468TV | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| DX337AM81S | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| ECU18C66Q7 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| J3W1NQQ2BZ | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| NBX892EA57 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| OT38R0N74H | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| RCE8XV9D25 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| SQM1449XO7 | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| VCX261B12R | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| WZU67V0H4I | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 27 of 27 studies
Australian industrial chemicals inventory status and applicable conditions.
Same-CAS cosmetic ingredient record for cross-vertical context.
Same-CAS food additive, ADI, and GRAS records where available.
E431 — ADI: 0-25 mg/kg bw mg/kg bw
View full food safety profile →Poly(oxy-1,2-ethanediyl), .alpha.-(1-oxooctadecyl)-.omega.-hydroxy- has 27 NOAEL studies in the database. The lowest reported value is 0 unitless via Ocular in Rabbit. Source: NTP ICE eye irritation.
Poly(oxy-1,2-ethanediyl), .alpha.-(1-oxooctadecyl)-.omega.-hydroxy- appears on 12 regulatory/inventory lists including children; Europe; Personal care, children; Europe; Personal care - general moisturizing - hand/body lotion, Europe; Personal care, and 9 more. Source: EPA CPDat.
Yes, Poly(oxy-1,2-ethanediyl), .alpha.-(1-oxooctadecyl)-.omega.-hydroxy- is also indexed as a cosmetic ingredient under the name PEG-100 Stearate. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, CosIng / Ingredients DB, EFSA / FDA GRAS. All data traces to primary regulatory sources and is updated from official government databases.
Poly(oxy-1,2-ethanediyl), .alpha.-(1-oxooctadecyl)-.omega.-hydroxy- also appears in cosmetics, food safety databases.