What is the NOAEL for 1,2-Dimethoxybenzene?
1,2-Dimethoxybenzene has 4 NOAEL studies in the database. The lowest reported value is 61WJZ2Q41I UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
1,2-Dimethoxybenzene
Also known as: EINECS 202-045-3, FEMA No. 3799, 2-Dimethoxybenzol, Brenzkatechindimethylether, Synthol (+4 more)
CAS 91-16-7
1,2-Dimethoxybenzene (CAS 91-16-7) is a chemical substance. Key regulatory status: REACH registered, 4 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
SOURCE
noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
4
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
15 fields
Name
1,2-Dimethoxybenzene
CAS Number
91-16-7
DTXSID
DTXSID7047065
Molecular Formula
C8H10O2
InChI Key
ABDKAPXRBAPSQN-UHFFFAOYSA-N
Monoisotopic Mass
138.06808
Synonyms
EINECS 202-045-3FEMA No. 37992-DimethoxybenzolBrenzkatechindimethyletherSyntholDimethylether pyrokatechinuUNII-61WJZ2Q41IMethyl guaiacolO,O-Dimethyl catechol
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
5 records
FragranceFlavouring and nutrient
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
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EPA CPDat
4 records
| List | Keyword | Source |
|---|---|---|
| IFRA Transparency | IFRA | IFRA |
| Europe | European Commission | Fl@vis |
| food_additive; Substances Added to Food (formerly EAFUS) (2/2019) | FDA | United States Food and Drug Administration (FDA) |
| consumer_product | P&G | Proctor & Gamble |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| 61WJZ2Q41I | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 61WJZ2Q41I | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 61WJZ2Q41I | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| 61WJZ2Q41I | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Veratrole | 202-045-3 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
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AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
SOURCE
CosIng / Ingredients DB
EU Status
permitted
Max
-
Category
Fragrance
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
1,2-DIMETHOXYBENZENE
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
1
Cannabis Data
Same-CAS cannabis compliance and lab records where available.
SOURCE
Cannabis regulatory / lab data
efsa substances
1 cannabis record found in efsa substances.
View full cannabis profile →Frequently Asked Questions
What regulatory lists include 1,2-Dimethoxybenzene?
1,2-Dimethoxybenzene appears on 4 regulatory/inventory lists including IFRA Transparency, Europe, food_additive; Substances Added to Food (formerly EAFUS) (2/2019), and 1 more. Source: EPA CPDat.
Is 1,2-Dimethoxybenzene used in cosmetics?
Yes, 1,2-Dimethoxybenzene is also indexed as a cosmetic ingredient under the name Veratrole. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 1,2-Dimethoxybenzene come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed, cannabis regulatory/lab databases. All data traces to primary regulatory sources and is updated from official government databases.
Is 1,2-Dimethoxybenzene used outside industrial chemicals?
1,2-Dimethoxybenzene also appears in cosmetics, pharmaceutical, cannabis databases.