What is the NOAEL for 2,3-Dihydroxynaphthalene?
2,3-Dihydroxynaphthalene has 4 NOAEL studies in the database. The lowest reported value is O9U131030Z UNII. Source: openFDA substances.
NOAEL Data
REACH Registered
Cosmetic Ingredient
2,3-Dihydroxynaphthalene
Also known as: 4-06-00-06564, BRN 0742375, 2,3-Dihydroxynapthalene, EINECS 202-156-7, UNII-O9U131030Z
CAS 92-44-4
2,3-Dihydroxynaphthalene (CAS 92-44-4) is a chemical substance. Key regulatory status: REACH registered, 3 regulatory/inventory lists, cosmetic ingredient cross-reference; source data from EPA ToxValDB, EPA CPDat, AICIS, ECHA REACH.
Cross-Vertical Regulatory Divergence
2,3-Dihydroxynaphthalene is prohibited in EU cosmetics but has active industrial GHS classifications (H302, H315, H318, H319, H335).
SOURCE
Cross-vertical comparison
Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
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noael studies public
NOAEL studies
4
SOURCE
chemical inventory jurisdictions
Regulatory lists
3
SOURCE
eu clp annex vi
GHS signal
Not classified
Chemical Identity
CAS, identifiers, formula, and alternate names for the matched substance record.
SOURCE
DSSTox identifiers
11 fields
Name
2,3-Dihydroxynaphthalene
CAS Number
92-44-4
DTXSID
DTXSID2043903
Molecular Formula
C10H8O2
InChI Key
JRNGUTKWMSBIBF-UHFFFAOYSA-N
Monoisotopic Mass
160.052429
Synonyms
4-06-00-06564BRN 07423752,3-DihydroxynapthaleneEINECS 202-156-7UNII-O9U131030Z
Functional Uses
Industrial and product-use categories associated with this substance.
SOURCE
EPA CPDat
2 records
Dye
Regulatory Lists
Inventory, screening, and regulatory list matches from public chemical databases.
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EPA CPDat
3 records
| List | Keyword | Source |
|---|---|---|
| banned; Europe; Personal care | European Commission | CosIng |
| Raw materials | Air Water INC | Air Water INC |
| Raw materials | Air Water INC | Air Water INC |
NOAEL Studies
Toxicology endpoints rendered from public NOAEL study rows.
SOURCE
NOAEL studies
Showing 4 of 4 studies
| Value | Unit | Endpoint | Route | Species | Source |
|---|---|---|---|---|---|
| O9U131030Z | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| O9U131030Z | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| O9U131030Z | UNII | FDA UNII substance identifier | - | - | openFDA substances |
| O9U131030Z | UNII | FDA UNII substance identifier | - | - | openFDA substances |
Showing 4 of 4 studies
REACH Registration
Registration status from the ECHA REACH registered substances database.
SOURCE
ECHA (EU)
1 records
| Status | Name | EC Number | Link |
|---|---|---|---|
| Registered | Naphthalene-2,3-diol | 202-156-7 | ECHA overview → |
Australian Status (AICIS)
Australian industrial chemicals inventory status and applicable conditions.
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AICIS inventory
1 records
Inventory Status
listed
Cosmetic Safety Profile
Same-CAS cosmetic ingredient record for cross-vertical context.
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CosIng / Ingredients DB
EU Status
prohibited
Max
-
Category
Colorant
Pharmaceutical Data
Same-CAS pharmaceutical records from drug and bioactivity sources.
SOURCE
EMBL-EBI ChEMBL
CHEMBL205007
ChEMBL Phase
Not listed
Adverse Events
0
Bioactivity
0
Frequently Asked Questions
What regulatory lists include 2,3-Dihydroxynaphthalene?
2,3-Dihydroxynaphthalene appears on 2 regulatory/inventory lists including banned; Europe; Personal care, Raw materials. Source: EPA CPDat.
Is 2,3-Dihydroxynaphthalene used in cosmetics?
Yes, 2,3-Dihydroxynaphthalene is also indexed as a cosmetic ingredient under the name 2,3-Naphthalenediol. View the full cosmetic safety profile on the ingredient page for detailed safety data, SCCS opinions, and regulatory status.
Where does the safety data for 2,3-Dihydroxynaphthalene come from?
Safety data is sourced from EPA ToxValDB, EPA CPDat, AICIS (Australian Industrial Chemicals Introduction Scheme), EPA DSSTox, ECHA REACH, CosIng / Ingredients DB, ChEMBL / DailyMed. All data traces to primary regulatory sources and is updated from official government databases.
Does 2,3-Dihydroxynaphthalene have different safety status in cosmetics vs industrial chemicals?
2,3-Dihydroxynaphthalene is prohibited in EU cosmetics but has active industrial GHS classifications (H302, H315, H318, H319, H335).
Is 2,3-Dihydroxynaphthalene used outside industrial chemicals?
2,3-Dihydroxynaphthalene also appears in cosmetics, pharmaceutical databases.