Is 2,3-Naphthalenediol safe in cosmetics?
2,3-Naphthalenediol has a safety rating of "POOR" in our database. EU status: prohibited. US status: permitted. This ingredient has been reviewed by cir.
2,3-Naphthalenediol
Also known as: 4-06-00-06564, BRN 0742375, 2,3-Dihydroxynapthalene, EINECS 202-156-7, UNII-O9U131030Z
INCI: 2,3-NAPHTHALENEDIOL
2,3-Naphthalenediol (CAS 92-44-4) is a cosmetic cosmetic ingredient functioning as Hair dye (oxidative). EU Regulation 1223/2009 status: prohibited; 1 safety opinion reviewed (cir). Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 92-44-4 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
2,3-Naphthalenediol is prohibited in EU cosmetics but has active industrial GHS classifications (H302, H315, H318, H319, H335).
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Hair dye (oxidative)
Safety Rating
POOR
Chemistry & Identifiers
IUPAC Name
naphthalene-2,3-diol
InChIKey
JRNGUTKWMSBIBF-UHFFFAOYSA-N
Regulatory Status
EU EU Status
prohibited
US US Status
permitted
US Notes
CIR concluded insufficient data to support safety; safety not substantiated
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for 2,3-Naphthalenediol.
Calculate MoS for your specific formulation with the MoS Calculator.
Safety Opinions
Official safety assessments from the Scientific Committee on Consumer Safety (SCCS) and Cosmetic Ingredient Review (CIR).
cir
Number 3, 1988
Verdict: unknown
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
1 - 10 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
EU CosIng Annex Listing
European Commission CosIng database Annex references per Regulation (EC) No 1223/2009.
Annex II — Prohibited
Ref: 1213
(EC) 2009/1223
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
SA Saudi SFDA (II - Prohibited)
BRIN Brazil/India Cosmetics
Brazil: Prohibited
India: Prohibited (GNRAS)
Additional Jurisdictional Restrictions (1)
| Jurisdiction | Status | Max % | Product Type |
|---|---|---|---|
| KR | prohibited | - | - |
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Dye
Regulatory List Membership (2)
EU Banned in Cosmetics
EU CosIng Cosmetics Ingredient Database
Expert Verdict
Expert safety assessment and concern-level summary for 2,3-Naphthalenediol.
Regulatory Flags
potential-allergen
eu_banned_cosmetics
eu_cosing_listed
Known Synonyms
4-06-00-06564
BRN 0742375
2,3-Dihydroxynapthalene
EINECS 202-156-7
UNII-O9U131030Z
Chemical Function
Dye
Regulatory Lists
banned; Europe; Personal care
Raw materials
Raw materials
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL205007
Frequently Asked Questions
Is 2,3-Naphthalenediol allowed in the EU?
2,3-Naphthalenediol EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does 2,3-Naphthalenediol do in cosmetics?
2,3-Naphthalenediol functions as: Hair dye (oxidative). It is classified as a cosmetic ingredient in our database. CAS number: 92-44-4.
Is 2,3-Naphthalenediol used outside cosmetics?
2,3-Naphthalenediol also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does 2,3-Naphthalenediol have different safety status in cosmetics vs industrial chemicals?
2,3-Naphthalenediol is prohibited in EU cosmetics but has active industrial GHS classifications (H302, H315, H318, H319, H335).
Compliance Tools
Check 2,3-Naphthalenediol compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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